Methanone, (2-iodophenyl)(4-methoxyphenyl)-

Base Information

• Chemical Name: Methanone, (2-iodophenyl)(4-methoxyphenyl)-
• CAS No.: 138504-32-2
• Molecular Formula: C14H11IO2
• Molecular Weight: 338.145
• Mol file: 138504-32-2.mol

Synonyms:

Chemical Property of Methanone, (2-iodophenyl)(4-methoxyphenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanone, (2-iodophenyl)(4-methoxyphenyl)-

There total 13 articles about Methanone, (2-iodophenyl)(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-Iodobenzoic acid (88-67-5) + methoxybenzene (100-66-3) → (2-iodophenyl)(4-methoxyphenyl)methanone (138504-32-2)

Guidance literature:

With trifluoroacetic acid; trifluoroacetic anhydride; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.tetlet.2018.01.026

Reference yield: 88.0%

2-bromo-4'-methoxy-benzophenone (59142-63-1) → (2-iodophenyl)(4-methoxyphenyl)methanone (138504-32-2)

Guidance literature:

With copper(l) iodide; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane; sodium iodide; In 1,4-dioxane; at 125 ℃; for 48h; Sealed tube;

DOI:10.1002/adsc.201300746

Reference yield: 80.0%

2-Iodobenzoyl chloride (609-67-6) + methoxybenzene (100-66-3) → (2-iodophenyl)(4-methoxyphenyl)methanone (138504-32-2)

Guidance literature:

With aluminum (III) chloride; at 80 ℃; for 8h; Inert atmosphere;

DOI:10.1021/acs.orglett.7b00716

upstream raw materials:

2-Iodobenzoic acid

methoxybenzene

2-bromo-α-(4-methoxyphenyl)benzyl alcohol

2-bromo-4'-methoxy-benzophenone