3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide

Base Information

Chemical Name:3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide
CAS No.:199666-03-0
Molecular Formula:C17H15N3O6S2
Molecular Weight:421.455
Hs Code.:
European Community (EC) Number:694-353-3
DSSTox Substance ID:DTXSID20415218
Nikkaji Number:J925.582F
Wikidata:Q27116332
Pharos Ligand ID:5SCP6VJCDZU3
Metabolomics Workbench ID:70585
ChEMBL ID:CHEMBL134915
Mol file:199666-03-0.mol

Synonyms:Ro 61-8048;Ro-61-8048;Ro-61-8048 sulfonamide

Suppliers and Price of 3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ro 61-8048
50mg
$ 305.00

Sigma-Aldrich
Ro 61-8048 ≥98% (HPLC)
25mg
$ 423.00

Sigma-Aldrich
Ro 61-8048 ≥98% (HPLC)
5mg
$ 107.00

Sigma-Aldrich
KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem
10 mg
$ 135.00

Sigma-Aldrich
KMO Inhibitor I, Ro 61-8048
10mg-m
$ 135.00

J&W Pharmlab
3,4-Dimethoxy-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-benzenesulfonamide 97%
50mg
$ 350.00

J&W Pharmlab
3,4-Dimethoxy-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-benzenesulfonamide 97%
10mg
$ 80.00

DC Chemicals
Ro 61-8048 >98%
1 g
$ 1500.00

CSNpharm
Ro 61-8048
25mg
$ 117.00

CSNpharm
Ro 61-8048
50mg
$ 187.00

Total 32 raw suppliers

Chemical Property of 3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide

Chemical Property:

Vapor Pressure:1.17E-15mmHg at 25°C
Melting Point:185℃
Boiling Point:627.4°Cat760mmHg
PKA:6.29±0.10(Predicted)
Flash Point:333.3°C
PSA：159.96000
Density:1.471g/cm³
LogP:5.21330
Storage Temp.:Store at +4°C
Solubility.:DMSO: ≥15mg/mL
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:6
Exact Mass:421.04022755
Heavy Atom Count:28
Complexity:638

Purity/Quality:

99%, ^*data from raw suppliers

Ro 61-8048 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25-36
Safety Statements: 26-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)S(=O)(=O)NC2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-])OC
Uses Ro 61-8048 is a potent and competitive kynurenine 3-monooxygenase (KMO) inhibitor.

Technology Process of 3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide

There total 2 articles about 3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.2%