Formaldehyde phenylhydrazone

Base Information

• Chemical Name: Formaldehyde phenylhydrazone
• CAS No.: 6228-40-6
• Molecular Formula: C7H8 N2
• Molecular Weight: 120.154
• NSC Number: 65257
• DSSTox Substance ID: DTXSID60289899
• Nikkaji Number: J2.135.165B
• Wikidata: Q82027430
• Mol file: 6228-40-6.mol

Synonyms:formaldehyde phenylhydrazone;6228-40-6;NSC65257;Methanal, phenylhydrazone;NCIOpen2_000403;SCHEMBL4282436;DTXSID60289899;FWTFCJFGBSEGFO-UHFFFAOYSA-N;NSC-65257

Chemical Property of Formaldehyde phenylhydrazone

Chemical Property:

• Vapor Pressure: 0.427mmHg at 25°C
• Boiling Point: 195.1°Cat760mmHg
• Flash Point: 71.8°C
• Density: 0.96g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 120.068748264
• Heavy Atom Count: 9
• Complexity: 84.9

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=NNC1=CC=CC=C1

Technology Process of Formaldehyde phenylhydrazone

There total 12 articles about Formaldehyde phenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + phenylhydrazine (100-63-0) → formaldehyde phenylhydrazone (6228-40-6)

Guidance literature:

With potassium tert-butylate; ammonium acetate; tetra-(n-butyl)ammonium iodide; In methanol; at 20 ℃; for 6h; Reagent/catalyst;

DOI:10.1021/acs.joc.8b01808

Reference yield: 79.0%

trimethyl indium (3385-78-2) + benzenediazonium o-benzenedisulfonimide → o-benzenedisulfonimide (4482-01-3) + formaldehyde phenylhydrazone (6228-40-6)

Guidance literature:

In tetrahydrofuran; at 20 - 25 ℃;

DOI:10.1002/ejoc.200700931

Reference yield: 76.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + phenylhydrazine hydrochloride (59-88-1) → 3-phenyl-1,3,4-thiadiazolidine + N-phenyl-(perhydro-1,3,5-dithiazin-5-yl)amine + formaldehyde phenylhydrazone (6228-40-6)

Guidance literature:

formaldehyd; With hydrogen sulfide; In water;

phenylhydrazine hydrochloride; In water; at 0 ℃; pH=3.15 - 3.20;

DOI:10.1007/s11172-006-0493-7

upstream raw materials:

formaldehyd

acetic acid

phenylhydrazine

styrene

Downstream raw materials:

phenylazomethane

formaldehyd

4-hydroxy-5-methyl-1-phenylpyrazole

methyl 4-phenylazobutanoate

Refernces

• 1、 Plater, M John. "Shaken, not stirred: a schools test for aldehydes and ketones". . p. 104 - 107. Retrieved 2019/11/22.
• 2、 Yang, Na,Yuan, Gaoqing. "A Multicomponent Electrosynthesis of 1,5-Disubstituted and 1-Aryl 1,2,4-Triazoles". . p. 11963 - 11969. Retrieved 2018/09/25.