Benzoic acid, (2E)-(1-phenylethylidene)hydrazide

Base Information

• Chemical Name: Benzoic acid, (2E)-(1-phenylethylidene)hydrazide
• CAS No.: 14850-97-6
• Molecular Formula: C15H14N2O
• Molecular Weight: 238.289
• Mol file: 14850-97-6.mol

Synonyms:

Chemical Property of Benzoic acid, (2E)-(1-phenylethylidene)hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, (2E)-(1-phenylethylidene)hydrazide

There total 19 articles about Benzoic acid, (2E)-(1-phenylethylidene)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzoic acid hydrazide (613-94-5) + acetophenone (98-86-2) → acetophenone N-benzoylhydrazone (14850-97-6)

Guidance literature:

In ethanol; for 6h; Reflux;

DOI:10.1021/ja504813r

Reference yield: 98.0%

benzoic acid hydrazide (613-94-5) + phenylacetylene (536-74-3) → acetophenone N-benzoylhydrazone (14850-96-5,14850-97-6,1219-41-6)

Guidance literature:

With C₈₃H₆₄AuF₆N₃O₆S₂; In chlorobenzene; at 60 ℃; for 18h; Solvent; Reagent/catalyst; Catalytic behavior; Schlenk technique;

DOI:10.3762/BJOC.16.175

Reference yield: 97.0%

benzoic acid hydrazide (613-94-5) + phenylacetylene (536-74-3) → acetophenone N-benzoylhydrazone (14850-97-6)

Guidance literature:

With silver hexafluoroantimonate; C₃₅H₄₁Au₂Cl₂N₅; In chlorobenzene; at 95 ℃; for 6h; Reagent/catalyst; Solvent;

DOI:10.1002/aoc.5942

upstream raw materials:

benzoic acid hydrazide

acetophenone

N-Benzoyl-N-trifylhydrazin

(1-bromoethyl)benzne

Downstream raw materials:

N′-(1-phenylethyl)benzohydrazide

(R)-(1-methyl-1-phenyl-but-3-enyl)amine

(R)-(+)-1-phenyl-1-(2-benzoylhydrazino)ethane

1-(4-methoxyphenyl)ethanone

Refernces

• 1、 Ajayeoba, Temitope A.,Woods, Joseph O.,Ayeni, Ayowole O.,Ajayi, Tomilola J.,Akeem, Raji A.,Hosten, Eric C.,Akinyele, Olawale F.. "Synthesis, crystallographic, computational and molecular docking studies of new acetophenone-benzoylhydrazones". . . Retrieved 2021/04/15.
• 2、 Chauhan, Prakashsingh M.,Morja, Mayur I.,Asamdi, Manjoorahmed,Chikhalia, Kishor H.. "Copper catalyzed cyanomethylation reaction of 4-thiazolidinone". supporting information. . Retrieved 2020/11/17.