Acetic acid, (5-methoxy-2-nitrophenoxy)-, ethyl ester

Base Information

Chemical Name:Acetic acid, (5-methoxy-2-nitrophenoxy)-, ethyl ester
CAS No.:157067-43-1
Molecular Formula:C11H13NO6
Molecular Weight:255.227
Hs Code.:
DSSTox Substance ID:DTXSID10470952
Wikidata:Q82299270
Mol file:157067-43-1.mol

Synonyms:157067-43-1;Acetic acid, (5-methoxy-2-nitrophenoxy)-, ethyl ester;DTXSID10470952

Suppliers and Price of Acetic acid, (5-methoxy-2-nitrophenoxy)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Acetic acid, (5-methoxy-2-nitrophenoxy)-, ethyl ester

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:255.07428713
Heavy Atom Count:18
Complexity:290

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)COC1=C(C=CC(=C1)OC)[N+](=O)[O-]

Technology Process of Acetic acid, (5-methoxy-2-nitrophenoxy)-, ethyl ester

There total 1 articles about Acetic acid, (5-methoxy-2-nitrophenoxy)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 704-14-3
3-methoxy-6-nitro-phenol

: 105-36-2
ethyl bromoacetate

: 157067-43-1
ethyl 5-methoxy-2-nitrophenoxyacetate

Guidance literature:: 3-methoxy-6-nitro-phenol; With potassium hydroxide; In ethanol; for 1h;

ethyl bromoacetate; In N,N-dimethyl-formamide; for 24h; Further stages.;
DOI:10.1021/jf062709g

Reference yield: 70.0%

: 157067-43-1
ethyl 5-methoxy-2-nitrophenoxyacetate

: 69884-05-5
4-hydroxy-7-methoxy-(2H)-1,4-benzoxazin-3(4H)-one

Guidance literature:: With sodium tetrahydroborate; palladium on activated charcoal; In 1,4-dioxane; water;
DOI:10.1021/jf062709g

Reference yield:

: 157067-43-1
ethyl 5-methoxy-2-nitrophenoxyacetate

: 15893-52-4,147802-15-1,147802-16-2,588716-65-8
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one

Guidance literature:: Multi-step reaction with 4 steps

1: NaBH₄ / Pt-C / methanol; H₂O / 1 h / 25 °C

2: LDA / toluene; hexane / 3 h / -70 °C

3: MCPBA / CH₂Cl₂ / 2 h / -5 °C

4: Bu₄NF*3H₂O / tetrahydrofuran / 2 h / 25 °C

With sodium tetrahydroborate; tetrabutyl ammonium fluoride; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; platinum on activated charcoal; In tetrahydrofuran; methanol; hexane; dichloromethane; water; toluene;
DOI:10.1016/S0040-4039(00)73347-8