6-BROMO-4-PHENYLQUINAZOLIN-2(1H)-ONE

Base Information

Chemical Name:6-BROMO-4-PHENYLQUINAZOLIN-2(1H)-ONE
CAS No.:33443-53-7
Molecular Formula:C14H9BrN2O
Molecular Weight:301.142
Hs Code.:2933990090
Mol file:33443-53-7.mol

Synonyms:2(1H)-Quinazolinone,6-bromo-4-phenyl;6-bromo-4-phenylquinazolin-2-ol;4-Phenyl-6-bromo-2(1H)-quinazolinone;6-Bromo-4-phenylquinazolin-2-one;6-Bromo-4-phenyl-2(1H)-quinazolinone;6-bromo-4-phenylquinazolin-2(1H)-one;4-Phenyl-6-brom-chinazolinon;6-bromo-4-phenyl-2-quinazolinone;

Suppliers and Price of 6-BROMO-4-PHENYLQUINAZOLIN-2(1H)-ONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
6-Bromo-4-phenyl-1H-quinazolin-2-one 95%+
5g
$ 1728.00

Matrix Scientific
6-Bromo-4-phenyl-1H-quinazolin-2-one 95%+
2.500g
$ 1144.00

Matrix Scientific
6-Bromo-4-phenyl-1H-quinazolin-2-one 95%+
1g
$ 524.00

Crysdot
6-Bromo-4-phenylquinazolin-2(1H)-one 97%
1g
$ 441.00

Chemenu
6-Bromo-4-phenylquinazolin-2(1H)-one 95+%
1g
$ 416.00

American Custom Chemicals Corporation
6-BROMO-4-PHENYL-1H-QUINAZOLIN-2-ONE 95.00%
5MG
$ 497.82

Total 7 raw suppliers

Chemical Property of 6-BROMO-4-PHENYLQUINAZOLIN-2(1H)-ONE

Chemical Property:

Melting Point:324-326℃ (N,N-dimethylformamide )
Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：46.01000
Density:1.57g/cm³
LogP:3.76490

Purity/Quality:

NLT 98% ^*data from raw suppliers

6-Bromo-4-phenyl-1H-quinazolin-2-one 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-BROMO-4-PHENYLQUINAZOLIN-2(1H)-ONE

There total 5 articles about 6-BROMO-4-PHENYLQUINAZOLIN-2(1H)-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 39263-32-6
2-amino-5-bromobenzonitrile

: 79-22-1
methyl chloroformate

: 100-58-3
phenylmagnesium bromide

: 33443-53-7
6-bromo-4-phenylquinazolin-2(1H)-one

Guidance literature:: 2-amino-5-bromobenzonitrile; phenylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 20 - 70 ℃; for 2h; Inert atmosphere;

methyl chloroformate; In tetrahydrofuran; diethyl ether; at 70 ℃; for 15h; Inert atmosphere;
DOI:10.1016/j.bmcl.2017.07.032

Reference yield: 68.0%

: 39859-36-4
2-amino-5-bromobenzophenone

: 57-13-6
urea

: 33443-53-7
6-bromo-4-phenylquinazolin-2(1H)-one

Guidance literature:: With acetic acid; at 140 ℃; for 24h; Microwave irradiation; Sealed tube;
DOI:10.3390/molecules25061467

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 39263-32-6
2-amino-5-bromobenzonitrile

: 541-41-3
chloroformic acid ethyl ester

: 33443-53-7
6-bromo-4-phenylquinazolin-2(1H)-one

Guidance literature:: bromobenzene; 2-amino-5-bromobenzonitrile; With magnesium; In tetrahydrofuran; at 80 ℃; for 3h; Schlenk technique; Inert atmosphere;

chloroformic acid ethyl ester; In tetrahydrofuran; at 0 ℃; for 10h; Reflux; Schlenk technique; Inert atmosphere;
DOI:10.1002/cjoc.202000045