Triaminomonochloro platinum (II) chloride

Base Information

• Chemical Name: Triaminomonochloro platinum (II) chloride
• CAS No.: 13815-16-2
• Molecular Formula: ClH6N3Pt-3
• Molecular Weight: 317.078
• Mol file: 13815-16-2.mol

Synonyms:2,3,4-triaminopyridine;triaminopyridine;Pyridin-2,3,4-triyltriamin;2,3,4-pyridinetriamine;pyridine-2,3,4-triyltriamine;

Chemical Property of Triaminomonochloro platinum (II) chloride

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 78.06000
• Density: g/cm³
• LogP: 1.01610
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 312.958672
• Heavy Atom Count: 6
• Complexity: 3.2

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: [NH2-].[NH2-].[NH2-].[Cl-].[Cl-].[Pt+2]

Technology Process of Triaminomonochloro platinum (II) chloride

There total 19 articles about Triaminomonochloro platinum (II) chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

transplatin (26035-31-4,14913-33-8,15663-27-1) → triamminechloroplatinum(II) chloride (13815-16-2)

Guidance literature:

With hydrogenchloride; ammonium hydroxide; silver nitrate; In water; N,N-dimethyl-formamide; byproducts: AgCl; Pt-complex reacted with a soln. of AgNO3 in DMF overnight; filtered; aq. NH4OH added; evapd. to dryness; dissolved in aq. HCl; concentrated; ethanol added; cooled to -20°C; pptd.; recrystd. from 0.1 M HCl/ethanol; elem. anal.;

DOI:10.1021/ja00035a033

Reference yield:

cisplatin (15663-27-1) → triamminechloroplatinum(II) chloride (13815-16-2)

Guidance literature:

With potassium cyanate; In water; byproducts: NH3; effect of KCNO;;

Reference yield:

{Pt(a3Cl)}Cl2 → triamminechloroplatinum(II) chloride (13815-16-2)

Guidance literature:

With H; In not given; formation at reduction of cis-(Pt(NH3)4Cl2) with H;;

upstream raw materials:

cisplatin

hydrogenchloride

tetraammineplatinum(II) chloride monohydrate

ammonia

Downstream raw materials:

{Pta3aq}(NO3)2

platinum

((NH₃)3Pt)3(NH₂NNCCOC₂NNCHC₂H₅)⁽⁵⁺⁾*5NO₃^(1-)*4H₂O=((NH₃)3Pt)3(NH₂NCNCOC₂NNC₂H₅CH)(NO₃)5*4H₂O

(NH₃)3Pt(NH₂NNHCCOC₂NNCHC₂H₅)⁽²⁺⁾*2NO₃^(1-)*2H₂O=Pt(NH₃)3(NH₂CNNHCOC₂NNCHC₂H₅)(NO₃)2*2H₂O

Refernces

• 1、 King, H. J. S.. "-". . . Retrieved 1948.
• 2、 Keck,Lippard. "Unwinding of supercoiled DNA by platinum-ethidium and related complexes". . p. 3386 - 3390. Retrieved 1992.