2-Isopropyl-5-methylcyclohexyl(trimethylsilyl) ether

Base Information

• Chemical Name: 2-Isopropyl-5-methylcyclohexyl(trimethylsilyl) ether
• CAS No.: 18419-38-0
• Molecular Formula: C₁₃H₂₈OSi
• Molecular Weight: 228.45
• Mol file: 18419-38-0.mol

Synonyms:(+/-)-menthyloxytrimethylsilane;menthol trimethylsilyl ether;(2-isopropyl-5-methylcyclohexyloxy)trimethylsilane;2-iso-propyl-5-methyl-cyclohexyloxytrimethysilane;methyltrimethylsilyl ether;Menthoxy-trimethyl-silan;

Chemical Property of 2-Isopropyl-5-methylcyclohexyl(trimethylsilyl) ether

Chemical Property:

• Boiling Point: 180 - 182 °C (760 mmHg)
• PSA: 9.23000
• LogP: 4.29870

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Isopropyl-5-methylcyclohexyl(trimethylsilyl) ether

There total 28 articles about 2-Isopropyl-5-methylcyclohexyl(trimethylsilyl) ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(-)-menthol (2216-51-5) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → (-)-menthol trimethylsilyl ether (18419-38-0,62338-23-2,88390-70-9,122999-13-7,66808-39-7)

Guidance literature:

iodine; In dichloromethane; at 20 ℃; for 0.0666667h;

DOI:10.1021/jo005519s

Reference yield: 98.0%

menthol (89-78-1) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → (2-isopropyl-5-methylcyclohexyloxy)trimethylsilane (62338-23-2,66808-39-7,88390-70-9,122999-13-7,18419-38-0)

Guidance literature:

With 1,3-dichloro-5,5-dimethylhydantoin; In dichloromethane; acetonitrile; at 20 ℃; for 0.5h;

DOI:10.1002/jccs.200900037

Reference yield: 95.0%

3-(trimethylsilyl)-2-oxazolidinone (43112-38-5) + 2-Isopropyl-5-methyl-cyclohexanol (89-78-1,490-99-3,491-01-0,491-02-1,1490-04-6,2216-51-5,2216-52-6,3623-51-6,3623-52-7,3623-53-8,15356-60-2,15356-70-4,20747-49-3,20752-33-4,20752-34-5,23283-97-8,64282-88-8) → dimethylenecyclourethane (497-25-6) + (2-isopropyl-5-methylcyclohexyloxy)trimethylsilane (62338-23-2,66808-39-7,88390-70-9,122999-13-7,18419-38-0)

Guidance literature:

trifluorormethanesulfonic acid; at 15 ℃; for 0.00833333h;

upstream raw materials:

3-(trimethylsilyl)-2-oxazolidinone

menthol

2-Isopropyl-5-methyl-cyclohexanol

1,1,1,3,3,3-hexamethyl-disilazane

Downstream raw materials:

2-(menthyl)-2-methyl-4H-1,3-benzodioxin-4-one

2-isopropyl-5-methylcyclohexyl acetate

menthyl formate

Menthone