2,4(1H,3H)-Pyrimidinedione, 1-((3-chloro-4-methoxyphenyl)methyl)-6-((2-hydroxyethyl)amino)-3-methyl-

Base Information

Chemical Name:2,4(1H,3H)-Pyrimidinedione, 1-((3-chloro-4-methoxyphenyl)methyl)-6-((2-hydroxyethyl)amino)-3-methyl-
CAS No.:121593-79-1
Molecular Formula:C₁₅H₁₈ClN₃O₄
Molecular Weight:339.779
Hs Code.:
DSSTox Substance ID:DTXSID30153311

Synonyms:BRN 3567509;2,4(1H,3H)-Pyrimidinedione, 1-((3-chloro-4-methoxyphenyl)methyl)-6-((2-hydroxyethyl)amino)-3-methyl-;121593-79-1;DTXSID30153311;LS-135134

Suppliers and Price of 2,4(1H,3H)-Pyrimidinedione, 1-((3-chloro-4-methoxyphenyl)methyl)-6-((2-hydroxyethyl)amino)-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,4(1H,3H)-Pyrimidinedione, 1-((3-chloro-4-methoxyphenyl)methyl)-6-((2-hydroxyethyl)amino)-3-methyl-

Chemical Property:

Vapor Pressure:1.99E-11mmHg at 25°C
Boiling Point:514.9°Cat760mmHg
Flash Point:265.2°C
Density:1.41g/cm³
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:339.0985838
Heavy Atom Count:23
Complexity:485

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=O)C=C(N(C1=O)CC2=CC(=C(C=C2)OC)Cl)NCCO

Technology Process of 2,4(1H,3H)-Pyrimidinedione, 1-((3-chloro-4-methoxyphenyl)methyl)-6-((2-hydroxyethyl)amino)-3-methyl-

There total 3 articles about 2,4(1H,3H)-Pyrimidinedione, 1-((3-chloro-4-methoxyphenyl)methyl)-6-((2-hydroxyethyl)amino)-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.3%

: 121593-87-1
N¹-(3-chloro-4-methoxybenzyl)-N³-methyl-6-chlorouracil

: 141-43-5
ethanolamine

: 121593-79-1
1-(3-Chloro-4-methoxy-benzyl)-6-(2-hydroxy-ethylamino)-3-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: In ethanol; water; for 2h; Heating;
DOI:10.1007/BF00831702

Reference yield:

: 13719-57-8
3-chloro-4-methoxybenzyl chloride

: 121593-79-1
1-(3-Chloro-4-methoxy-benzyl)-6-(2-hydroxy-ethylamino)-3-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 71.3 percent / K₂CO₃ / dimethylsulfoxide / 1 h / 80 - 90 °C

2: 97.3 percent / ethanol; H₂O / 2 h / Heating

With potassium carbonate; In ethanol; water; dimethyl sulfoxide;
DOI:10.1007/BF00831702

Reference yield:

: 4318-56-3
3-methyl-6-chlorouracil

: 121593-79-1
1-(3-Chloro-4-methoxy-benzyl)-6-(2-hydroxy-ethylamino)-3-methyl-1H-pyrimidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 71.3 percent / K₂CO₃ / dimethylsulfoxide / 1 h / 80 - 90 °C

2: 97.3 percent / ethanol; H₂O / 2 h / Heating

With potassium carbonate; In ethanol; water; dimethyl sulfoxide;
DOI:10.1007/BF00831702