4-(Ethoxymethyl)-2-methoxyphenol

Base Information

• Chemical Name: 4-(Ethoxymethyl)-2-methoxyphenol
• CAS No.: 13184-86-6
• Molecular Formula: C10H14O3
• Molecular Weight: 182.219
• Hs Code.: 2909500000
• European Community (EC) Number: 236-136-4
• UNII: 1423UFT5P6
• DSSTox Substance ID: DTXSID3074783
• Nikkaji Number: J213.731C
• Wikidata: Q27251558
• Metabolomics Workbench ID: 47857
• Mol file: 13184-86-6.mol

Synonyms:vanillyl ethyl ether

Chemical Property of 4-(Ethoxymethyl)-2-methoxyphenol

Chemical Property:

• Appearance/Colour: pale amber to yellow liquid with a phenolic, smoky odour
• Vapor Pressure: 0.00308mmHg at 25°C
• Refractive Index: 1.517
• Boiling Point: 275.167 °C at 760 mmHg
• Flash Point: 120.217 °C
• PSA: 38.69000
• Density: 1.088 g/cm³
• LogP: 1.93730
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 182.094294304
• Heavy Atom Count: 13
• Complexity: 138

Purity/Quality:

98% ^*data from raw suppliers

4-(Ethoxymethyl)-2-methoxyphenol >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOCC1=CC(=C(C=C1)O)OC

Technology Process of 4-(Ethoxymethyl)-2-methoxyphenol

There total 8 articles about 4-(Ethoxymethyl)-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.56%

chloroethane (75-00-3) + vanillin (121-33-5,8014-42-4) → phenol, 4-(ethoxymethyl)-2-methoxy- (13184-86-6)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 30 - 40 ℃; for 4h;

Reference yield: 98.0%

ethanol (64-17-5) + vanillin (121-33-5,8014-42-4) → phenol, 4-(ethoxymethyl)-2-methoxy- (13184-86-6)

Guidance literature:

With hydrogen; at 30 ℃; for 24h; under 11251.1 Torr; Autoclave; Industrial scale;

Reference yield: 97.0%

ethanol (64-17-5) + 4-hydroxymethyl-2-methoxyphenol (498-00-0) → phenol, 4-(ethoxymethyl)-2-methoxy- (13184-86-6)

Guidance literature:

at 80 ℃; for 2h; Neat (no solvent);

upstream raw materials:

4-hydroxymethyl-2-methoxyphenol

vanillin

l'α-chloro α-ethoxymethyltributyletain

ethanol