Morpholine, 4-(2-methyl-1-propenyl)-

Base Information

• Chemical Name: Morpholine, 4-(2-methyl-1-propenyl)-
• CAS No.: 2403-55-6
• Molecular Formula: C8H15 N O
• Molecular Weight: 141.213
• Hs Code.: 2934999090
• European Community (EC) Number: 683-719-8
• NSC Number: 526662
• UNII: MXJ75MRH9H
• DSSTox Substance ID: DTXSID6062385
• Nikkaji Number: J24.519D
• Mol file: 2403-55-6.mol

Synonyms:Morpholine, 4-(2-methyl-1-propenyl)-;2403-55-6;2-Methyl-1-morpholinopropene;4-(2-methylprop-1-en-1-yl)morpholine;2-Methyl-1-morpholino-1-propene;4-(2-methylprop-1-enyl)morpholine;Morpholine, 4-(2-methylpropenyl)-;1-Morpholino-2-methylpropene;4-(2-Methylpropenyl)morpholine;4-(2-Methyl-1-propenyl)morpholine;MXJ75MRH9H;Morpholine, 4-(2-methyl-1-propen-1-yl)-;NSC-526662;isobutenylmorpholine;NSC526662;4-Isocrotylmorpholine;1-Morpholino-isobutene;N-Isobutenyl morpholine;UNII-MXJ75MRH9H;1-morpholino-1-isobutene;1-MORPHOLINOISOBUTENE;SCHEMBL1760699;DTXSID6062385;4-(2-Methyl-propenyl)-morpholine;1-morpholino-2-methyl-prop-1-ene;N-(2-Methyl-1-propenyl)morpholine;MFCD00023373;AKOS024332291;NSC 526662

Chemical Property of Morpholine, 4-(2-methyl-1-propenyl)-

Chemical Property:

• Vapor Pressure: 0.143mmHg at 25°C
• Boiling Point: 216°Cat760mmHg
• PKA: 6.00±0.50(Predicted)
• Flash Point: 62°C
• PSA: 12.47000
• Density: 1.003g/cm³
• LogP: 1.18020
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 141.115364102
• Heavy Atom Count: 10
• Complexity: 121

Purity/Quality:

99% ^*data from raw suppliers

4-(2-METHYLPROP-1-EN-1-YL)MORPHOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=CN1CCOCC1)C

Technology Process of Morpholine, 4-(2-methyl-1-propenyl)-

There total 2 articles about Morpholine, 4-(2-methyl-1-propenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

morpholine (110-91-8,99108-56-2) + Isobutyronitrile (78-82-0) → N-isobutylmorpholine (10315-98-7) + 4-(2-methyl-1-propenyl)morpholine (2403-55-6)

Guidance literature:

With nickel; hydrogen; at 70 ℃; for 16h; under 760.051 Torr;

DOI:10.1134/S107036321604006X

Reference yield:

3,3-dimethyl-2-morpholin-4-yl-4-phenyl-cyclobutane-1,1-dicarbonitrile (41274-76-4) → 4-(2-methyl-1-propenyl)morpholine (2403-55-6) + Benzylidenemalononitrile (2700-22-3)

Guidance literature:

In dichloromethane; at -20 ℃; Further Variations:; Temperatures; concentrations; Kinetics; Equilibrium constant;

DOI:10.1021/jo0344182

Reference yield: 93.0%

4-(2-methyl-1-propenyl)morpholine (2403-55-6) → 4-morpholinecarboxaldehyde (4394-85-8) + acetone (67-64-1)

Guidance literature:

With oxygen; Cu-X zeolite; In 1,2-dichloro-ethane; acetonitrile; at 50 ℃; for 5h;

DOI:10.1039/b001515f

upstream raw materials:

3,3-dimethyl-2-morpholin-4-yl-4-phenyl-cyclobutane-1,1-dicarbonitrile

morpholine

Isobutyronitrile

Downstream raw materials:

N-isobutylmorpholine

4-(2,2-dimethyl-4-pyridin-4-yl-cyclobutyl)-morpholine

6,6-dimethyl-7-morpholin-4-yl-3-phenyl-3-aza-bicyclo[3.2.0]heptane-2,4-dione

2,2,6,6-tetramethyl-7-morpholin-4-yl-5-phenyl-6,7-dihydro-5H-pyrano[2,3-d][1,3]dioxin-4-one