10315-98-7

Usage

Uses

Used in Oil and Gas Industry:
N-Isobutylmorpholine is used as a corrosion inhibitor in water-based drilling fluids for preventing the corrosion of metal equipment in oil and gas wells. It achieves this by forming a protective film on metal surfaces, which shields them from the corrosive effects of water and other substances.
Used in Industrial Water Treatment:
N-Isobutylmorpholine is utilized as an additive in industrial water treatment processes to prevent the formation of scale and corrosion in boilers and cooling systems, thereby enhancing the efficiency and longevity of these systems.

InChI:InChI=1/C8H17NO/c1-8(2)7-9-3-5-10-6-4-9/h8H,3-7H2,1-2H3

Upstream product

• 110-91-8 morpholine 
• 78-84-2 isobutyraldehyde 
• 2403-55-6 4-(2-methyl-1-propenyl)morpholine 
• 78-77-3 Isobutyl bromide 
• 75-30-9 2-iodo-propane 
• 50-00-0 formaldehyd 
• 18071-39-1 2-methyl-1-(4-morpholinyl)propan-1-one 
• 78-82-0 Isobutyronitrile 
• 78-83-1 2-methyl-propan-1-ol 
• 513-36-0 isobutyryl chloride 
• 1708-29-8 2,5-dihydrofuran 
• 78-81-9 isobutylamine 

Relevant academic research and scientific papers

Reductive amination of ketones/aldehydes with amines using BH3N(C2H5)3as a reductant

Herein, we report the first example of efficient reductive amination of ketones/aldehydes with amines using BH3N(C2H5)3 as a catalyst and a reductant under mild conditions, affording various tertiary and secondary amines in excellent yields. A mechanistic study indicates that BH3N(C2H5)3 plays a dual function role of promoting imine and iminium formation and serving as a reductant in reductive amination. This journal is

Ionic liquid/H2O-mediated synthesis of mesoporous organic polymers and their application in methylation of amines

Mesoporous Tr?ger's base-functionalized polymers (Meso-TBPs) were prepared using a sulfonic acid group functionalized ionic liquid/H2O system, with surface areas up to 431 m2 g-1 and pore sizes of 3-15 nm. Ir(ii) coordinated Meso-TBPs exhibited extraordinary catalytic performance in the N-methylation of amines using methanol.

Colloid and nanosized catalysts in organic synthesis: XIV. Reductive amination and amidation of carbonitriles catalyzed by nickel nanoparticles

Hydrogenation of carbonitriles catalyzed by nickel nanoparticles in the presence of primary amines led to the predominant formation of unsymmetrical secondary amines. In the presence of secondary amines hydrogenation of nitrites provided enamines as main products. Hydrogenation of nitriles in the presence of formamide or acetamide afforded formyl or acetyl derivatives of primary amines.

Colloid and nanosized catalysts in organic synthesis: IX hydrogenation of enamines with hydrogen at atmospheric pressure

Hydrogenation of enamines with hydrogen at atmospheric pressure was performed using nickel nanoparticles as a catalyst. The reaction may be used to produce tertiary amines under mild conditions using an accessible catalyst.

Catalytic hydrogenation of amides to amines under mild conditions

Under (not so much) pressure: A general method for the hydrogenation of tertiary and secondary amides to amines with excellent selectivity using a bimetallic Pd-Re catalyst has been developed. The reaction proceeds under low pressure and comparatively low temperature. This method provides organic chemists with a simple and reliable tool for the synthesis of amines. Copyright

Leishmanicidal potential of N-substituted morpholine derivatives: Synthesis and structure-activity relationships

A series of N-substituted morpholines 2-20 was synthesised by reacting various acid chlorides and alkyl halides with morpholine (1). All of the synthesised compounds 2-20 were screened for their leishmanicidal effects using amphotericin B (IC50 = 0.24 μg L-1) and pentamidine (IC50 = 2.56 μg mL-1) as standards and a structure-activity relationship (SAR) study was established. The compounds 2 (IC50 = 48 μg mL-1), 3 (IC50 = 30.0 μg mL-1), 10 (IC50 = 41.0 μg mL-1), 15 (IC50 = 33.0 μg mL-1), 16 (IC50 = 35.0 μg mL-1) and 20 (IC50 = 47.0 μg mL-1) showed weak leishmanicidal activities.

Aminomethylation of organic halides promoted by zinc in protic medium

Organic halides undergo smooth aminomethylation by secondary amines and aqueous formaldehyde promoted by metallic zinc under copper(I) catalysis. Good to excellent yields are obtained with primary, secondary, and tertiary iodides, allylic, propargylic, and benzylic bromides and with α-bromoesters. In most cases, DMSO is the best solvent, but dioxane is preferable for some more reactive halides. Additional experiments with radical quenchers and promoters and the use of 'radical clocks' indicate a stepwise reaction mechanism initiated by the attack of an alkyl radical to iminium ion.

A novel aminomethylation reaction of gaseous alkanes with tert-methylamine N-oxides via C-H bond activation by copper(II) salts

The Cu(OAc)2/CF3COOH (TFA) system catalyzes the aminomethylation of gaseous alkanes such as propane and ethane with trimethylamine N-oxide to give N,N-dimethylisobutylamine (1) and N,N-dimethylpropylamine (7), respectively.The corresponding trifluoroacetates are also formed as by-products from the reactions of methane and propane. Keywords: Copper acetate; Aminomethylation; Amine N-oxide; C-H bond activation; C-C bond formation; Alkane