3-Benzylidenepiperazine-2,5-dione

Base Information

Chemical Name:3-Benzylidenepiperazine-2,5-dione
CAS No.:19459-03-1
Molecular Formula:C11H10N2O2
Molecular Weight:202.213
Hs Code.:
DSSTox Substance ID:DTXSID90395230
Mol file:19459-03-1.mol

Synonyms:3-benzylidenepiperazine-2,5-dione;19459-03-1;2,5-Piperazinedione, 3-(phenylmethylene)-, (Z)-;DTXSID90395230

Suppliers and Price of 3-Benzylidenepiperazine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-Benzylidenepiperazine-2,5-dione

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:202.074227566
Heavy Atom Count:15
Complexity:304

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)NC(=CC2=CC=CC=C2)C(=O)N1

Technology Process of 3-Benzylidenepiperazine-2,5-dione

There total 6 articles about 3-Benzylidenepiperazine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 30166-29-1,30166-30-4,41808-11-1
1-acetyl-3-[(Z)-benzylidene]-2,5-piperazinedione

: 19459-03-1
(Z)-3-phenylmethylenepiperazine-2,5-dione

Guidance literature:: With hydrazine hydrate; In N,N-dimethyl-formamide; for 2h; Ambient temperature;

Reference yield: 81.0%

: 3027-05-2
N,N'-diacetylpiperazin-2,5-dione

: 100-52-7
benzaldehyde

: 19459-03-1
(Z)-3-phenylmethylenepiperazine-2,5-dione

Guidance literature:: N,N'-diacetylpiperazin-2,5-dione; benzaldehyde; With potassium tert-butylate; In dichloromethane; tert-butyl alcohol; at 30 ℃; for 6h;

With hydrazine hydrate; In dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol; at 20 ℃; for 2h;
DOI:10.1021/acs.orglett.1c01894