Ethyl 1-methyl-3-((methyl-2-pyridinylamino)sulfonyl)-1H-pyrazole-4-carboxylate

Base Information

Chemical Name:Ethyl 1-methyl-3-((methyl-2-pyridinylamino)sulfonyl)-1H-pyrazole-4-carboxylate
CAS No.:178880-02-9
Molecular Formula:C₁₃H₁₆N₄O₄S
Molecular Weight:324.36
Hs Code.:
DSSTox Substance ID:DTXSID20939126
Nikkaji Number:J762.285F
Wikidata:Q82915573
Mol file:178880-02-9.mol

Synonyms:178880-02-9;Ethyl 1-methyl-3-((methyl-2-pyridinylamino)sulfonyl)-1H-pyrazole-4-carboxylate;Ethyl 1-methyl-3-(N-methyl-N-2'-pyridyl)sufamoylpyrazole-4-carboxylate;ethyl 1-methyl-3-[methyl(pyridin-2-yl)sulfamoyl]pyrazole-4-carboxylate;1H-Pyrazole-4-carboxylic acid, 1-methyl-3-((methyl-2-pyridinylamino)sulfonyl)-, ethyl ester;ethyl 1-methyl-3-(methylpyridin-2-ylsulfamoyl)pyrazole-4-carboxylate;DTXSID20939126;WAGWOIHAQQCHGF-UHFFFAOYSA-N;LS-128347;Ethyl 1-methyl-3-[methyl(pyridin-2-yl)sulfamoyl]-1H-pyrazole-4-carboxylate;1-Methyl-3-[methyl(2-pyridinyl)sulfamoyl]-1H-pyrazole-4-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 1-methyl-3-((methyl-2-pyridinylamino)sulfonyl)-1H-pyrazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ethyl 1-methyl-3-((methyl-2-pyridinylamino)sulfonyl)-1H-pyrazole-4-carboxylate

Chemical Property:

Vapor Pressure:9.62E-11mmHg at 25°C
Boiling Point:515.7°Cat760mmHg
Flash Point:265.7°C
PSA：102.77000
Density:1.36g/cm³
LogP:1.89770
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:324.08922618
Heavy Atom Count:22
Complexity:493

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN(N=C1S(=O)(=O)N(C)C2=CC=CC=N2)C

Technology Process of Ethyl 1-methyl-3-((methyl-2-pyridinylamino)sulfonyl)-1H-pyrazole-4-carboxylate

There total 3 articles about Ethyl 1-methyl-3-((methyl-2-pyridinylamino)sulfonyl)-1H-pyrazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 178880-00-7
ethyl 1-methyl-3-(N-2'-pyridyl)sulfamoylpyrazole-4-carboxylate

: 74-88-4
methyl iodide

: 178880-02-9
ethyl 1-methyl-3-(N-methyl-N-2'-pyridyl)sulfamoylpyrazole-4-carboxylate

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 72h; Ambient temperature;
DOI:10.1002/ardp.19963290503

Reference yield:

: 504-29-0
2-aminopyridine

: 178880-02-9
ethyl 1-methyl-3-(N-methyl-N-2'-pyridyl)sulfamoylpyrazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / tetrahydrofuran / 2 h / Heating

2: 78 percent / NaH / dimethylformamide / 72 h / Ambient temperature

With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/ardp.19963290503

Reference yield:

: 93621-38-6
ethyl 3-chlorosulfonyl-1-methylpyrazole-4-carboxylate

: 178880-02-9
ethyl 1-methyl-3-(N-methyl-N-2'-pyridyl)sulfamoylpyrazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / tetrahydrofuran / 2 h / Heating

2: 78 percent / NaH / dimethylformamide / 72 h / Ambient temperature

With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/ardp.19963290503