(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one

Base Information

Chemical Name:(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one
CAS No.:218614-14-3
Molecular Formula:C20H44O3Si2
Molecular Weight:388.739
Hs Code.:
DSSTox Substance ID:DTXSID90460371
Wikidata:Q82284398
Mol file:218614-14-3.mol

Synonyms:218614-14-3;(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one;(4S)-4,6-bis[[tert-butyl(dimethyl)silyl]oxy]-3,3-dimethylhexan-2-one;(4S)-4,6-Bis-[(tert-butyldimethylsilyl)oxy]-3,3-dimethylhexan-2-one;DTXSID90460371;AKOS025294921;J-014325;(4S)-4, 6-bis[[tert-butyl(dimethyl)silyl]oxy]-3, 3-dimethylhexan-2-one

Suppliers and Price of (4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one
5g
$ 1100.00

Medical Isotopes, Inc.
(4S)-4,6-Bis-[[tert-butyldimethylsilyl)oxy]]-3,3-dimethylhexan-2-one
2.5 g
$ 2000.00

Medical Isotopes, Inc.
(4S)-4,6-Bis-[[tert-butyldimethylsilyl)oxy]]-3,3-dimethylhexan-2-one
500 mg
$ 875.00

Biosynth Carbosynth
(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one
2 g
$ 750.80

Biosynth Carbosynth
(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one
1 g
$ 413.00

Biosynth Carbosynth
(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one
500 mg
$ 230.00

Biosynth Carbosynth
(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one
250 mg
$ 125.00

Biosynth Carbosynth
(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one
5 g
$ 1365.00

AK Scientific
(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one
2g
$ 1063.00

Total 3 raw suppliers

Chemical Property of (4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one

Chemical Property:

Vapor Pressure:1.86E-06mmHg at 25°C
PSA：35.53000
LogP:6.40390
Solubility.:Dichloromethane, Ether, Ethyl Acetate, Hexane
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:10
Exact Mass:388.28289833
Heavy Atom Count:25
Complexity:455

Purity/Quality:

98%Min ^*data from raw suppliers

(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C(C)(C)C(CCO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C
Isomeric SMILES:CC(=O)C(C)(C)[C@H](CCO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C

Technology Process of (4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one

There total 10 articles about (4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1822-00-0
trimethylsilylmethyllithium

: 218614-13-2
(-)-methyl (3S)-3,5-bis{[tert-butyl(dimethyl)silyl]oxy}-2,2-dimethylpentanoate

: 218614-14-3
(4S)-4,6-bis{[tert-butyl(dimethyl)silyl]oxy}-3,3-dimethylhexan-2-one

Guidance literature:: In pentane; at 0 ℃; for 3.5h;
DOI:10.1002/chem.200305669

Reference yield: 100.0%

: 4,6-bis-(tert-butyl-dimethyl-silanyloxy)-3,3-dimethyl-1-trimethylsilanyl-hexan-2-one

: 218614-14-3
(4S)-4,6-bis{[tert-butyl(dimethyl)silyl]oxy}-3,3-dimethylhexan-2-one

Guidance literature:: With Amberlite IRC-50; at 20 ℃; for 1.25h;
DOI:10.1002/anie.200351413

Reference yield:

: 89922-82-7
3-(tert-butyldimethylsilanyloxy)propionaldehyde

: 218614-14-3
(4S)-4,6-bis{[tert-butyl(dimethyl)silyl]oxy}-3,3-dimethylhexan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 77 percent / BH₃*THF / tetrahydrofuran / 0.25 h / 20 °C

2: 100 percent / diethylamino-polystyrene / CH₂Cl₂ / 2.5 h / 0 °C

3: 100 percent / pentane / 3.5 h / 0 °C

With borane-THF; diethylamino-polystyrene; In tetrahydrofuran; dichloromethane; pentane;
DOI:10.1002/chem.200305669