Diethyl 4-ethoxyphenylmalonate

Base Information

Chemical Name:Diethyl 4-ethoxyphenylmalonate
CAS No.:23197-69-5
Molecular Formula:C15H20O5
Molecular Weight:280.321
Hs Code.:2918990090
DSSTox Substance ID:DTXSID10574121
Wikidata:Q82463047
Mol file:23197-69-5.mol

Synonyms:DIETHYL 4-ETHOXYPHENYLMALONATE;23197-69-5;diethyl 2-(4-ethoxyphenyl)propanedioate;SCHEMBL10719216;DTXSID10574121;LQSBAEXJSFLVHM-UHFFFAOYSA-N;Diethyl (4-ethoxyphenyl)propanedioate;AKOS011681663

Suppliers and Price of Diethyl 4-ethoxyphenylmalonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Diethyl4-Ethoxyphenylmalonate
2g
$ 970.00

Biosynth Carbosynth
Diethyl 4-ethoxyphenylmalonate
2 g
$ 1092.00

Biosynth Carbosynth
Diethyl 4-ethoxyphenylmalonate
1 g
$ 600.60

Biosynth Carbosynth
Diethyl 4-ethoxyphenylmalonate
500 mg
$ 335.00

Biosynth Carbosynth
Diethyl 4-ethoxyphenylmalonate
250 mg
$ 182.50

Biosynth Carbosynth
Diethyl 4-ethoxyphenylmalonate
100 mg
$ 100.00

Total 4 raw suppliers

Chemical Property of Diethyl 4-ethoxyphenylmalonate

Chemical Property:

PSA：61.83000
LogP:2.29510
Solubility.:Chloroform, Ethyl Acetate, Methanol
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:280.13107373
Heavy Atom Count:20
Complexity:289

Purity/Quality:

97% ^*data from raw suppliers

Diethyl4-Ethoxyphenylmalonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=C(C=C1)C(C(=O)OCC)C(=O)OCC
Uses Diethyl 4-Ethoxyphenylmalonate (cas# 23197-69-5) is a compound useful in organic synthesis.

Technology Process of Diethyl 4-ethoxyphenylmalonate

There total 3 articles about Diethyl 4-ethoxyphenylmalonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 40784-88-1
ethyl 4-ethoxyphenylacetate

: 95-92-1
oxalic acid diethyl ester

: 23197-69-5
diethyl (4-ethoxyphenyl)malonate

Guidance literature:: With sodium ethanolate; In ethanol; at 190 - 200 ℃; for 0.5h; under 15 Torr;
DOI:10.1246/bcsj.57.3173

Reference yield:

: 699-08-1
1-ethoxy-4-iodobenzene

: 105-53-3
diethyl malonate

: 23197-69-5
diethyl (4-ethoxyphenyl)malonate

Guidance literature:: With copper(l) iodide; caesium carbonate; 2-Phenylphenol; for 17h; Heating;
DOI:10.1039/b608012j

Reference yield:

: 156-38-7
4-hydroxyphenylacetate

: 23197-69-5
diethyl (4-ethoxyphenyl)malonate

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / ethanol

2: 70 percent / C₂H₅ONa / ethanol / 0.5 h / 190 - 200 °C / 15 Torr

With potassium hydroxide; sodium ethanolate; In ethanol;
DOI:10.1246/bcsj.57.3173