ethyl 2-oxopiperidine-4-carboxylate

Base Information

Chemical Name:ethyl 2-oxopiperidine-4-carboxylate
CAS No.:25410-09-7
Molecular Formula:C8H13NO3
Molecular Weight:171.19400
Hs Code.:
Mol file:25410-09-7.mol

Synonyms:2-oxo-piperidine-4-carboxylic acid;2-oxopiperidine-4-carboxylic acid ethyl ester;4-Piperidinecarboxylic acid,2-oxo;4-Ethoxycarbonyl-2-piperidone;4-carboethoxypiperidone;

Suppliers and Price of ethyl 2-oxopiperidine-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of ethyl 2-oxopiperidine-4-carboxylate

Chemical Property:

Boiling Point:326.0±35.0 °C(Predicted)
PKA:15.71±0.40(Predicted)
PSA：58.89000
Density:1.118±0.06 g/cm3(Predicted)
LogP:0.35160

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 2-oxopiperidine-4-carboxylate

There total 3 articles about ethyl 2-oxopiperidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

: 1313498-26-8
1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate

: 25410-09-7
ethyl 2-oxopiperidine-4-carboxylate

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 1h;

Reference yield:

: 142851-03-4
1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate

: 25410-09-7
ethyl 2-oxopiperidine-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium periodate; ruthenium(IV) oxide hydrate / acetonitrile; water / 1.5 h / 20 - 35 °C

2: hydrogenchloride / dichloromethane; 1,4-dioxane / 1 h

With hydrogenchloride; sodium periodate; ruthenium(IV) oxide hydrate; In 1,4-dioxane; dichloromethane; water; acetonitrile;