1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate

Base Information

Chemical Name:1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate
CAS No.:1313498-26-8
Molecular Formula:C₁₃H₂₁NO₅
Molecular Weight:271.313
Hs Code.:

Synonyms:

Suppliers and Price of 1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Ethyl1-Boc-2-oxopiperidine-4-carboxylate
25g
$ 728.00

AK Scientific
Ethyl1-Boc-2-oxopiperidine-4-carboxylate
10g
$ 397.00

Total 3 raw suppliers

Chemical Property of 1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate

Chemical Property:

Boiling Point:390.3±35.0 °C(Predicted)
Density:1.152±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

Ethyl1-Boc-2-oxopiperidine-4-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate

There total 1 articles about 1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.6%

: 142851-03-4
1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate

: 1313498-26-8
1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate

Guidance literature:: With sodium periodate; ruthenium (IV) oxide monohydrate; In water; acetonitrile; at 20 - 35 ℃; for 2h;

Reference yield: 94.5%

: 1313498-26-8
1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate

: 25410-09-7
ethyl 2-oxopiperidine-4-carboxylate

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 1h;

Reference yield:

: 1313498-26-8
1-tert-butyl 4-ethyl 2-oxopiperidine-1,4-dicarboxylate

: 1620564-29-5
4-(8-amino-3-(3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-7-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)benzamide

Guidance literature:: Multi-step reaction with 10 steps

1: hydrogenchloride / dichloromethane; 1,4-dioxane / 1 h / 20 °C

2: Lawessons reagent / toluene / 2 h / Inert atmosphere; Reflux

3: mercury(II) diacetate / tetrahydrofuran / 2 h / 20 - 60 °C / Cooling with ice

4: lithium hydroxide monohydrate / tetrahydrofuran / 2 h / 20 °C

5: phosgene / tetrahydrofuran; N,N-dimethyl-formamide / 1 h / 0 °C

6: N-ethyl-N,N-diisopropylamine / tetrahydrofuran; N,N-dimethyl-formamide / 1 h / 60 °C

7: N,N-dimethyl-formamide; trichlorophosphate / acetonitrile / 0.08 h / 0 - 70 °C

8: N-Bromosuccinimide / N,N-dimethyl-formamide / 0.17 h / Cooling with ice

9: ammonia / isopropyl alcohol / 24 h / 100 °C / Sealed tube

10: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate / water; 1,4-dioxane / 2 h / 90 °C / Inert atmosphere

With Lawessons reagent; hydrogenchloride; phosgene; N-Bromosuccinimide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; lithium hydroxide monohydrate; mercury(II) diacetate; ammonia; potassium carbonate; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; trichlorophosphate; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol; toluene; acetonitrile;