4-(4-Formyl-2-methoxy-5-nitrophenoxy)butanoic acid

Base Information

Chemical Name:4-(4-Formyl-2-methoxy-5-nitrophenoxy)butanoic acid
CAS No.:263758-69-6
Molecular Formula:C12H13NO7
Molecular Weight:283.238
Hs Code.:
European Community (EC) Number:845-457-4

Synonyms:4-(4-formyl-2-methoxy-5-nitrophenoxy)butanoic acid;263758-69-6;SCHEMBL4185655;EN300-1091038;Z415630944

Suppliers and Price of 4-(4-Formyl-2-methoxy-5-nitrophenoxy)butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-(4-Formyl-2-methoxy-5-nitrophenoxy)butanoic acid

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:283.06920175
Heavy Atom Count:20
Complexity:354

Purity/Quality:: 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)C=O)[N+](=O)[O-])OCCCC(=O)O

Technology Process of 4-(4-Formyl-2-methoxy-5-nitrophenoxy)butanoic acid

There total 6 articles about 4-(4-Formyl-2-methoxy-5-nitrophenoxy)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 219931-67-6
ethyl 4-(4-formyl-2-methoxy-5-nitrophenoxy)butanoate

: 263758-69-6
4-(4-formyl-2-methoxy-5-nitrophenoxy)butanoic acid

Guidance literature:: With trifluoroacetic acid; In water; at 90 ℃; for 3h; Inert atmosphere;
DOI:10.1021/ja305280w

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 263758-69-6
4-(4-formyl-2-methoxy-5-nitrophenoxy)butanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / K₂CO₃, n-Bu₄NI / acetonitrile / 2 h / Heating

2: 99 percent / LiOH / dioxane / 8 h / Ambient temperature

3: fuming HNO₃, AcOH / 6 h

With lithium hydroxide; nitric acid; tetra-(n-butyl)ammonium iodide; potassium carbonate; acetic acid; In 1,4-dioxane; acetonitrile;
DOI:10.1021/jo951550w

Reference yield:

: 176375-41-0
4-(4-formyl-2-methoxyphenoxy)butanoic acid methyl ester

: 263758-69-6
4-(4-formyl-2-methoxy-5-nitrophenoxy)butanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / LiOH / dioxane / 8 h / Ambient temperature

2: fuming HNO₃, AcOH / 6 h

With lithium hydroxide; nitric acid; acetic acid; In 1,4-dioxane;
DOI:10.1021/jo951550w