ETHYL 2-[(4-METHOXYPHENYL)SULFANYL]ACETATE

Base Information

• Chemical Name: ETHYL 2-[(4-METHOXYPHENYL)SULFANYL]ACETATE
• CAS No.: 28743-98-8
• Molecular Formula: C11H14O3S
• Molecular Weight: 226.296
• Mol file: 28743-98-8.mol

Synonyms:

Chemical Property of ETHYL 2-[(4-METHOXYPHENYL)SULFANYL]ACETATE

Chemical Property:

• PSA: 60.83000
• LogP: 2.35040

Purity/Quality:

99% ^*data from raw suppliers

Ethyl 2-[(4-methoxyphenyl)thio]acetate >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ethyl 2-[(4-methoxyphenyl)sulfanyl]acetate is used as a reactant in the methylrhenium trioxide catalyzed reactions of ethyl diazoacetate and organic azides.

Technology Process of ETHYL 2-[(4-METHOXYPHENYL)SULFANYL]ACETATE

There total 15 articles about ETHYL 2-[(4-METHOXYPHENYL)SULFANYL]ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Methoxybenzenethiol (696-63-9) + ethyl bromoacetate (105-36-2) → (4-methoxy-phenylsulfanyl)-acetic acid ethyl ester (28743-98-8)

Guidance literature:

With potassium carbonate; In acetone; for 8h; Heating;

DOI:10.1021/jm0205548 DOI:10.1021/jm0205550

Reference yield: 95.0%

4-Methoxybenzenethiol (696-63-9) + chloroacetic acid ethyl ester (105-39-5) → (4-methoxy-phenylsulfanyl)-acetic acid ethyl ester (28743-98-8)

Guidance literature:

4-Methoxybenzenethiol; With sodium ethanolate; In ethanol; at 20 ℃; for 1h;

chloroacetic acid ethyl ester; In ethanol; for 3h; Reflux;

Reference yield: 95.0%

diazoacetic acid ethyl ester (623-73-4) + 4-Methoxybenzenethiol (696-63-9) → (4-methoxy-phenylsulfanyl)-acetic acid ethyl ester (28743-98-8)

Guidance literature:

In water; acetonitrile; at 20 ℃; for 6h; Irradiation;

DOI:10.1039/d0ob02006k

upstream raw materials:

sodium 4-methoxyphenylthiolate

ethyl bromoacetate

diazoacetic acid ethyl ester

4-Methoxybenzenethiol

Downstream raw materials:

Fluoro-(4-methoxy-phenylsulfanyl)-acetic acid ethyl ester

4-(4-Methoxy-benzenesulfonyl)-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-piperidin e-4-carboxylic acid ethyl ester

4-(4-Methoxy-benzenesulfonyl)-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-piperidine-4-carboxylic acid

4-(4-methoxybenzenesulfonyl)-1-(4-pyridin-2-ylbenzyl)piperidine-4-carboxylic acid ethyl ester