3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-8-phenethylnortropane maleate

Base Information

Chemical Name:3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-8-phenethylnortropane maleate
CAS No.:15620-19-6
Molecular Formula:C₄H₄O₄*C₃₀H₃₃NO
Molecular Weight:539.671
Hs Code.:

Synonyms:3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-8-phenethylnortropane maleate;1-alpha-H,5-alpha-H-Nortropane, 3-alpha-((10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-8-phenethyl-, maleate (1:1);15620-19-6;C30H33NO.C4H4O4;C30-H33-N-O.C4-H4-O4;LS-97493

Suppliers and Price of 3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-8-phenethylnortropane maleate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-8-phenethylnortropane maleate

Chemical Property:

Vapor Pressure:5.84E-12mmHg at 25°C
Boiling Point:545.6°Cat760mmHg
Flash Point:156.4°C
Density:g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:539.26717328
Heavy Atom Count:40
Complexity:681

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2CC(CC1N2CCC3=CC=CC=C3)OC4C5=CC=CC=C5CCC6=CC=CC=C46.C(=CC(=O)O)C(=O)O
Isomeric SMILES:C1C[C@H]2CC(C[C@@H]1N2CCC3=CC=CC=C3)OC4C5=CC=CC=C5CCC6=CC=CC=C46.C(=C\C(=O)O)\C(=O)O

Technology Process of 3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-8-phenethylnortropane maleate

There total 3 articles about 3-alpha-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)oxy)-8-phenethylnortropane maleate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 47702-79-4
3α-((10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy)-8α-phenetyl-8-azabicyclo[3.2.1]octane

: 110-16-7,26099-09-2
maleic acid

: 15620-19-6
3α-((10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy)-8α-phenetyl-8-azabicyclo[3.2.1]octane maleate

Guidance literature:: In diethyl ether;
DOI:10.1016/j.bmcl.2011.12.008

Reference yield:

: 120-29-6
3-tropanol

: 15620-19-6
3α-((10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy)-8α-phenetyl-8-azabicyclo[3.2.1]octane maleate

Guidance literature:: Multi-step reaction with 4 steps

1: toluene / 20 °C

2: potassium permanganate; potassium hydroxide / pyridine; water / 5 h / 20 °C / Cooling with ice

3: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 20 °C / Inert atmosphere

4: diethyl ether

With potassium permanganate; sodium tris(acetoxy)borohydride; potassium hydroxide; In pyridine; diethyl ether; water; 1,2-dichloro-ethane; toluene;
DOI:10.1016/j.bmcl.2011.12.008