6-METHOXY-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE

Base Information

• Chemical Name: 6-METHOXY-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE
• CAS No.: 5780-00-7
• Molecular Formula: C9H8 O4
• Molecular Weight: 180.16
• Hs Code.: 2932999099
• Mol file: 5780-00-7.mol

Synonyms:Benzaldehyde,2-methoxy-4,5-(methylenedioxy)- (6CI,7CI,8CI);2-Methoxy-4,5-(methylenedioxy)benzaldehyde; 6-Methoxypiperonal

Chemical Property of 6-METHOXY-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE

Chemical Property:

• Vapor Pressure: 0.000984mmHg at 25°C
• Melting Point: 109-115°C
• Boiling Point: 302.5°C at 760 mmHg
• Flash Point: 134.4°C
• PSA: 44.76000
• Density: 1.321g/cm³
• LogP: 1.23640
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

6-Methoxy-1,3-benzodioxole-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-METHOXY-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE

There total 13 articles about 6-METHOXY-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

5-methoxybenzo[d]1,3-dioxole (7228-35-5) + Dichloromethyl methyl ether (4885-02-3) → 2-methoxy-4,5-methylenedioxybenzaldehyde (5780-00-7)

Guidance literature:

With titanium tetrachloride; for 2h; Ambient temperature;

DOI:10.1021/jo00386a014

Reference yield: 93.0%

4,5-methylenedioxy-2-hydroxybenzaldehyde (4720-68-7) + dimethyl sulfate (77-78-1) → 2-methoxy-4,5-methylenedioxybenzaldehyde (5780-00-7)

Guidance literature:

With potassium carbonate; In benzine; for 48h; Reflux;

DOI:10.1016/j.ejmech.2015.09.009

Reference yield: 90.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 1-bromo-2-methoxy-4,5-methylenedioxybenzene (10022-35-2) → 2-methoxy-4,5-methylenedioxybenzaldehyde (5780-00-7)

Guidance literature:

With n-butyllithium;

upstream raw materials:

4,5-methylenedioxy-2-hydroxybenzaldehyde

dimethyl sulfate

5-methoxybenzo[d]1,3-dioxole

Dichloromethyl methyl ether

Downstream raw materials:

4-(6-methoxy-benzo[1,3]dioxol-5-ylmethylene)-2-phenyl-4H-oxazol-5-one

2-methoxy-4,5-methylenedioxyphenylmethyl alcohol

2-methoxy-4,5;3'4'-bis(methylenedioxy)chalcone

5-(1-hydroxy-4-pentenyl)-6-methoxy-1,3-benzodioxole