(R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate

Base Information

Chemical Name:(R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate
CAS No.:340129-94-4
Molecular Formula:C11H19NO2
Molecular Weight:197.277
Hs Code.:
Mol file:340129-94-4.mol

Synonyms:tert-butyl (2R)-2-vinylpyrrolidine-1-carboxylate;tert-butyl (2R)-2-vinyl-1-pyrrolidine carboxylate;(2R)-1-tert-butoxycarbonyl-2-vinylpyrrolidine;(R)-N-(tert-butoxycarbonyl)-2-ethenylpyrrolidine;1,1-dimethylethyl (2R)-2-ethenyl-1-pyrrolidinecarboxylate;

Suppliers and Price of (R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Aaron Chemicals
1-Pyrrolidinecarboxylicacid,2-ethenyl-,1,1-dimethylethylester,(2R)- 98%
1g
$ 282.00

Total 6 raw suppliers

Chemical Property of (R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate

Chemical Property:

PSA：29.54000
LogP:2.50980

Purity/Quality:

97% ^*data from raw suppliers

1-Pyrrolidinecarboxylicacid,2-ethenyl-,1,1-dimethylethylester,(2R)- 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate

There total 11 articles about (R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 593-60-2,25951-54-6
Vinyl bromide

: 86953-79-9
tert-butyl pyrrolidine-1-carboxylate

: 340129-94-4
(R)-1-[(1,1-dimethylethoxy)carbonyl]-2-ethenylpyrrolidine

: 115393-77-6
tert-butyl (S)-2-vinylpyrrolidine-1-carboxylate

Guidance literature:: tert-butyl pyrrolidine-1-carboxylate; With sec.-butyllithium; (-)-sparteine; In diethyl ether; at -78 ℃; for 1h;

With lithium chloride; In tetrahydrofuran; diethyl ether; at -78 ℃; for 1h;

Vinyl bromide; In tetrahydrofuran; diethyl ether; at -78 - 25 ℃; for 12h; Title compound not separated from byproducts;
DOI:10.1021/jo035845i

Reference yield:

: 593-66-8
vinyliodide

: 86953-79-9
tert-butyl pyrrolidine-1-carboxylate

: 340129-94-4
(R)-1-[(1,1-dimethylethoxy)carbonyl]-2-ethenylpyrrolidine

: 115393-77-6
tert-butyl (S)-2-vinylpyrrolidine-1-carboxylate

Guidance literature:: tert-butyl pyrrolidine-1-carboxylate; With sec.-butyllithium; (-)-sparteine; In diethyl ether; at -78 ℃; for 1h;

With lithium chloride; In tetrahydrofuran; diethyl ether; at -78 ℃; for 0.5h;

vinyliodide; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; Title compound not separated from byproducts;
DOI:10.1016/j.tet.2005.01.094

Reference yield:

: (Z)-6-((tert-butoxycarbonyl)amino)hex-2-en-1-ol

: 340129-94-4
(R)-1-[(1,1-dimethylethoxy)carbonyl]-2-ethenylpyrrolidine

: 115393-77-6
tert-butyl (S)-2-vinylpyrrolidine-1-carboxylate

Guidance literature:: With cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate; allyl (S)-6-(2-chloronaphthalen-1-yl)-5-methylpyridine-2-carboxylate; In N,N-dimethyl acetamide; at 100 ℃; for 1h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol203218d