2-Bromo-3-{[tert-butyl(dimethyl)silyl]oxy}-6-hydroxybenzenecarbaldehyde

Base Information

• Chemical Name: 2-Bromo-3-{[tert-butyl(dimethyl)silyl]oxy}-6-hydroxybenzenecarbaldehyde
• CAS No.: 347840-64-6
• Molecular Formula: C13H19BrO3Si
• Molecular Weight: 331.282
• Hs Code.: 2913000090
• Mol file: 347840-64-6.mol

Synonyms:2-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6-hydroxybenzaldehyde;AE-0054;2-Bromo-3-[(tert-butyldimethylsilyl)oxy]-6-hydroxybenzaldehyde;

Chemical Property of 2-Bromo-3-{[tert-butyl(dimethyl)silyl]oxy}-6-hydroxybenzenecarbaldehyde

Chemical Property:

• Melting Point: 44～46℃
• PSA: 46.53000
• LogP: 4.35120

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-3-[(tert-butyldimethylsilyl)oxy]-6-hydroxybenzaldehyde 95.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Bromo-3-{[tert-butyl(dimethyl)silyl]oxy}-6-hydroxybenzenecarbaldehyde

There total 2 articles about 2-Bromo-3-{[tert-butyl(dimethyl)silyl]oxy}-6-hydroxybenzenecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-Dihydroxybenzaldehyde (1194-98-5) → 2-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6-hydroxybenzaldehyde (347840-64-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / Br₂ / CHCl₃ / 3 h / 20 °C

2: 97 percent / imidazole / CH₂Cl₂ / 0.25 h / 20 °C

With 1H-imidazole; bromine; In dichloromethane; chloroform;

DOI:10.1016/j.tetlet.2005.11.150

Reference yield:

2,5-dimethoxybenzaldehyde (93-02-7) → 2-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6-hydroxybenzaldehyde (347840-64-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / BBr₃ / CH₂Cl₂ / 1 h / -78 - 0 °C

2: Br₂ / CHCl₃ / 20 °C

3: 10.64 g / imidazole / CH₂Cl₂ / 0.25 h / 20 °C

With 1H-imidazole; bromine; boron tribromide; In dichloromethane; chloroform;

DOI:10.1021/ja021396c

Reference yield: 72.0%

benzyl bromide (100-39-0) + 2-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6-hydroxybenzaldehyde (347840-64-6) → C20H25BrO3Si

Guidance literature:

With potassium carbonate; In ethanol; at 0 - 26 ℃; for 4h;

DOI:10.1055/s-0035-1561417

upstream raw materials:

2,5-Dihydroxybenzaldehyde

2,5-dimethoxybenzaldehyde

Downstream raw materials:

2-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6-methoxybenzaldehyde

2-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6-methoxybenzene-methanol

2-bromo-3-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-4-methoxyphenol

[[2-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6-methoxyphenyl]methoxy](1,1-dimethylethyl)diphenylsilane

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 347840-64-6 2-Bromo-3-{[tert-butyl(dimethyl)silyl]oxy}-6-hydroxybenzenecarbaldehyde

Send

Send

Metric Ton KG G Pound L ML

Send

Send