Tizoprolic

Base Information

• Chemical Name: Tizoprolic
• CAS No.: 30709-69-4
• Molecular Formula: C7H9NO2S
• Molecular Weight: 171.22
• Hs Code.: 2934100090
• Mol file: 30709-69-4.mol

Synonyms:2-Propyl-5-thiazolecarboxylicacid;RU 15350;2-Propyl-1,3-thiazole-5-carboxylic acid;

Chemical Property of Tizoprolic

Chemical Property:

• Vapor Pressure: 0.000196mmHg at 25°C
• Refractive Index: 1.568
• Boiling Point: 314.538 °C at 760 mmHg
• PKA: 3.78±0.10(Predicted)
• Flash Point: 144.027 °C
• PSA: 78.43000
• Density: 1.278 g/cm³
• LogP: 1.79380

Purity/Quality:

95+% ^*data from raw suppliers

2-Propylthiazole-5-carboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Tizoprolic

There total 2 articles about Tizoprolic which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-propyl-thiazole-5-carboxylate (50680-74-5) → 2-propyl-thiazole-5-carboxylic acid (30709-69-4)

Guidance literature:

With potassium hydroxide; In ethanol; for 0.333333h; Heating;

Reference yield:

→ 2-propyl-thiazole-5-carboxylic acid (30709-69-4)

Guidance literature:

Thiobutyramid, 1) Ethyl 2-chlor-3-oxo-propionat, 2) KOH;

Reference yield:

chloroformic acid ethyl ester (541-41-3) + 2-propyl-thiazole-5-carboxylic acid (30709-69-4) + 1-(2-aminoethyl)-4-(2-methoxyphenyl)piperazine (40255-48-9) → N-β-[4'-(o-methoxyphenyl)-1'-piperazinyl]-ethyl-2-n-propylthiazol-5-carboxamide (50831-96-4)

Guidance literature:

With triethylamine; In diethyl ether; water; acetone;

upstream raw materials:

ethyl 2-propyl-thiazole-5-carboxylate

Downstream raw materials:

N-β-[4'-(o-methoxyphenyl)-1'-piperazinyl]-ethyl-2-n-propylthiazol-5-carboxamide

N-δ-[4'-(o-methoxyphenyl)-1'-piperazinyl]-butyl-2-n-propylthiazol-5-carboxamide

N-methyl-N-β-[4'-(o-methoxyphenyl)-1'-piperazinyl]-ethyl-2-n-propylthiazol-5-carboxamide