Ethyl 2,2-difluoro-3-hydroxypropanoate

Base Information

Chemical Name:Ethyl 2,2-difluoro-3-hydroxypropanoate
CAS No.:380-41-6
Molecular Formula:C5H8F2O3
Molecular Weight:154.11200
Hs Code.:2918199090
European Community (EC) Number:695-285-7
Mol file:380-41-6.mol

Synonyms:ethyl 2,2-difluoro-3-hydroxypropanoate;380-41-6;2,2-Difluoro-3-hydroxy-propionic acid ethyl ester;Propanoic acid, 2,2-difluoro-3-hydroxy-, ethyl ester;ethyl 2,2-difluoro-3-hydroxypropionate;SCHEMBL936998;MFCD05864326;AKOS006293483;ethyl2,2-difluoro-3-hydroxypropanoate;SB36936;CS-0309335;EN300-176153;A936251

Suppliers and Price of Ethyl 2,2-difluoro-3-hydroxypropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Ethyl 2,2-difluoro-3-hydroxypropanoate 97%
1 g
$ 695.00

SynQuest Laboratories
Ethyl 2,2-difluoro-3-hydroxypropanoate 97%
250 mg
$ 495.00

J&W Pharmlab
2,2-Difluoro-3-hydroxy-propionicacidethylester 96%
50mg
$ 137.00

Crysdot
Ethyl2,2-difluoro-3-hydroxypropanoate 95+%
5g
$ 2183.00

Crysdot
Ethyl2,2-difluoro-3-hydroxypropanoate 95+%
1g
$ 545.00

Chemenu
ethyl2,2-difluoro-3-hydroxypropanoate 95%
1g
$ 514.00

Chemenu
ethyl2,2-difluoro-3-hydroxypropanoate 95%
5g
$ 2057.00

American Custom Chemicals Corporation
ETHYL 2,2-DIFLUORO-3-HYDROXYPROPIONATE 95.00%
1G
$ 939.89

AK Scientific
Ethyl2,2-difluoro-3-hydroxypropanoate
500mg
$ 951.00

Total 10 raw suppliers

Chemical Property of Ethyl 2,2-difluoro-3-hydroxypropanoate

Chemical Property:

Boiling Point:75-78°C/9mm
PSA：46.53000
LogP:0.17710
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:154.04415044
Heavy Atom Count:10
Complexity:124

Purity/Quality:

99% ^*data from raw suppliers

Ethyl 2,2-difluoro-3-hydroxypropanoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(CO)(F)F

Technology Process of Ethyl 2,2-difluoro-3-hydroxypropanoate

There total 6 articles about Ethyl 2,2-difluoro-3-hydroxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.8%

: 765-63-9
2,2,3,3-tetrafluorooxetane

: 64-17-5
ethanol

: 127-09-3
sodium acetate

: 380-41-6
ethyl 2,2-difluoro-3-hydroxypropanoate

Guidance literature:: 2,2,3,3-tetrafluorooxetane; ethanol; sodium acetate; at 45 - 70 ℃; for 2h; Reflux;

With sulfuric acid; for 8h; Reflux;

With sodium hydrogencarbonate; In water;