Diethylisopropylamine

Base Information

• Chemical Name: Diethylisopropylamine
• CAS No.: 6006-15-1
• Molecular Formula: C7H17 N
• Molecular Weight: 115.219
• European Community (EC) Number: 611-931-2
• DSSTox Substance ID: DTXSID40208785
• Nikkaji Number: J2.110.562G
• Wikidata: Q72461989
• Mol file: 6006-15-1.mol

Synonyms:Diethylisopropylamine;6006-15-1;N,N-diethylpropan-2-amine;N,N-Diethyl Isopropyl Amine;2-Propanamine, N,N-diethyl-;diethyl(propan-2-yl)amine;2-Propaneamine, N,N-diethyl-;2-Propanamine,N,N-diethyl-;iPrNEt2;diethyl isopropylamine;diethyl-isopropylamine;diethylisopropyl amine;i-PrNEt2;diethyl iso-propylamine;N(Et)2iPr;Diethyl-iso-propylamine;diethyl iso propyl amine;N,N-diethylisopropylamine;N, N-diethylisopropylamine;N,N-diethyl-isopropylamine;N,N-Diethyl-2-propanamine;SCHEMBL20811;N-isopropyl-N,N-diethylamine;N,N-Diethyl-2-propanamine #;DTXSID40208785;(i-C3H7)N(C2H5)2;AMY18859;AKOS028108670;FT-0701086;A904647

Chemical Property of Diethylisopropylamine

Chemical Property:

• Vapor Pressure: 30.4mmHg at 25°C
• Melting Point: 131-132℃
• Refractive Index: 1.4041
• Boiling Point: 104.7°Cat760mmHg
• PKA: 10.69±0.25(Predicted)
• Flash Point: 6°C
• PSA: 3.24000
• Density: 0.759g/cm³
• LogP: 1.73660
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 115.136099547
• Heavy Atom Count: 8
• Complexity: 46.3

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C(C)C

Technology Process of Diethylisopropylamine

There total 9 articles about Diethylisopropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethyl bromide (74-96-4) + isopropylamine (75-31-0) → N,N-diethyl-N-isopropylamine (6006-15-1)

Guidance literature:

With potassium carbonate; 1.) 0 deg C, 1 h, 2.) 25 deg C, 3 h;

DOI:10.1021/jo00077a046

Reference yield: 20.0%

diethylamine (109-89-7) + acetone (67-64-1) → N,N-diethyl-N-isopropylamine (6006-15-1)

Guidance literature:

With sodium tetrahydroborate; sulfuric acid; In isopropyl alcohol; at 20 - 30 ℃;

DOI:10.1007/BF02524364

Reference yield:

N-ethyl-2-propylacetamide (111757-38-1) → N,N-diethyl-N-isopropylamine (6006-15-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 5h; Heating;

DOI:10.1021/ja00155a021

upstream raw materials:

2-diethylamino-2-methylpropionitrile

diethylamine

isopropyl bromide

acetone

Downstream raw materials:

N-isopropylethylamine

acetaldehyde

diisopropyl sulfide

2,4-N,N'-bis(diethylamido)-2,4-dithioxo-1,3,2λ⁵,4λ⁵-dithiadiphosphetane

Refernces

• 1、 Zou, Qizhuang,Liu, Fei,Zhao, Tianxiang,Hu, Xingbang. "Reductive amination of ketones/aldehydes with amines using BH3N(C2H5)3as a reductant". supporting information. p. 8588 - 8591. Retrieved 2021/09/04.
• 2、 Brown, Jay H.,Bushweller, C. Hackett. "Stereodynamics of 2-(diethylamino)propane and 2-(dibenzylamino)propane. 1H and 13C{1H} DNMR studies. Molecular mechanics calculations". . p. 12567 - 12577. Retrieved 2007/10/03.