2,6-Diformyl-3,5-dimethoxyphenol

Base Information

• Chemical Name: 2,6-Diformyl-3,5-dimethoxyphenol
• CAS No.: 125666-65-1
• Molecular Formula: C10H10O5
• Molecular Weight: 210.186
• Hs Code.: 2912499000
• European Community (EC) Number: 802-114-3
• DSSTox Substance ID: DTXSID00378418
• Wikidata: Q82167925
• Mol file: 125666-65-1.mol

Synonyms:2,6-Diformyl-3,5-dimethoxyphenol;125666-65-1;2-Hydroxy-4,6-dimethoxyisophthalaldehyde;2-hydroxy-4,6-dimethoxybenzene-1,3-dicarbaldehyde;1,3-Benzenedicarboxaldehyde,2-hydroxy-4,6-dimethoxy-;DTXSID00378418;MFCD01632212;AKOS015837500;AB09489;BP-10153;CS-0212659;4-HYDROXY-2,6-DIMETHOXYISOPHTHALALDEHYDE;10.14272/KMBLGUFRZSQVSJ-UHFFFAOYSA-N.1;A890036;doi:10.14272/KMBLGUFRZSQVSJ-UHFFFAOYSA-N.1;J-005259

Chemical Property of 2,6-Diformyl-3,5-dimethoxyphenol

Chemical Property:

• Vapor Pressure: 1.84E-07mmHg at 25°C
• Melting Point: 214-218 °C
• Refractive Index: 1.607
• Boiling Point: 376.9 °C at 760 mmHg
• Flash Point: 150.8 °C
• PSA: 72.83000
• Density: 1.32 g/cm³
• LogP: 1.03440
• Storage Temp.: 2-8°C
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 210.05282342
• Heavy Atom Count: 15
• Complexity: 208

Purity/Quality:

97% ^*data from raw suppliers

2,6-Diformyl-3,5-dimethoxyphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C(=C1C=O)O)C=O)OC

Technology Process of 2,6-Diformyl-3,5-dimethoxyphenol

There total 3 articles about 2,6-Diformyl-3,5-dimethoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dimethoxyphenol (500-99-2) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2-hydroxy-4,6-dimethoxybenzaldehyde (708-76-9) + syringaldehyde (22080-96-2) + 2,6-diformyl-3,5-dimethoxyphenol (125666-65-1)

Guidance literature:

With trichlorophosphate; at 25 ℃; for 15h; Yield given. Yields of byproduct given;

DOI:10.1021/jo00299a011

Reference yield:

2-hydroxy-4,6-dimethoxybenzaldehyde (708-76-9) → 2,6-diformyl-3,5-dimethoxyphenol (125666-65-1)

Guidance literature:

With hydrogenchloride; aluminium trichloride; diethyl ether; Erwaermen des Reaktionsprodukts mit Wasser;

DOI:10.1007/BF00899029

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + aluminium trichloride (7446-70-0) + 2-hydroxy-4,6-dimethoxybenzaldehyde (708-76-9) + diethyl ether (60-29-7,927820-24-4) → 2,6-diformyl-3,5-dimethoxyphenol (125666-65-1)

Guidance literature:

Erhitzen des Reaktionsprodukts mit Wasser;

DOI:10.1007/BF00899029

upstream raw materials:

3,5-dimethoxyphenol

N,N-dimethyl-formamide

hydrogenchloride

aluminium trichloride

Downstream raw materials:

3,5-dimethoxy-2,6-dimethylphenol