4-HydroxyMelatonin

Base Information

Chemical Name:4-HydroxyMelatonin
CAS No.:39998-64-6
Molecular Formula:C₁₃H₁₆N₂O₃
Molecular Weight:248.282
Hs Code.:
Mol file:39998-64-6.mol

Synonyms:N-[2-(4-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide;

Suppliers and Price of 4-HydroxyMelatonin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
4-Hydroxymelatonin
5mg
$ 496.00

TRC
4-Hydroxymelatonin
2.5mg
$ 305.00

Medical Isotopes, Inc.
4-Hydroxymelatonin
2.5 mg
$ 750.00

Medical Isotopes, Inc.
4-Hydroxymelatonin
1 mg
$ 650.00

Total 3 raw suppliers

Chemical Property of 4-HydroxyMelatonin

Chemical Property:

Melting Point:>140°C (dec.)
Boiling Point:564.7±50.0 °C(Predicted)
PKA:8.31±0.50(Predicted)
PSA：74.35000
Density:1.266±0.06 g/cm3(Predicted)
LogP:1.95160
Storage Temp.:Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

4-Hydroxymelatonin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4-Hydroxymelatonin, is a metabolite of Melatonin (M215000), which is a hormone found in animals, plants, and microbes. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.

Technology Process of 4-HydroxyMelatonin

There total 2 articles about 4-HydroxyMelatonin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73-31-4
5-methoxy-N-acetyl-tryptamine

: 2208-41-5
6-hydroxymelatonin

: 188397-16-2
5-methoxy-3-[2-(N-acetylamino)ethyl]indol-2(3H)-one

: 39998-64-6
4-hydroxymelatonin

: 7,7'-bi(5-methoxy-N-acetyltryptamin-4-one)

Guidance literature:: With ferrous ammonium sulphate; edetate disodium; ascorbic acid; dihydrogen peroxide; In phosphate buffer; at 20 ℃; for 0.25h; pH=7.4; Further byproducts given;
DOI:10.1016/S0045-2068(02)00511-4