2-(4-Amino-3-nitrophenoxy)ethanol

Base Information

• Chemical Name: 2-(4-Amino-3-nitrophenoxy)ethanol
• CAS No.: 50982-74-6
• Molecular Formula: C8H10 N2 O4
• Molecular Weight: 198.18
• Hs Code.: 2922509090
• European Community (EC) Number: 621-658-0
• UNII: 540REY4Q17
• DSSTox Substance ID: DTXSID70198983
• Nikkaji Number: J78.139H
• Wikidata: Q27261149
• Mol file: 50982-74-6.mol

Synonyms:2-(4-Amino-3-nitrophenoxy)ethanol;50982-74-6;2-(4-amino-3-nitrophenoxy)ethan-1-ol;3-Nitro-4-aminophenoxyethanol;Ethanol, 2-(4-amino-3-nitrophenoxy)-;UNII-540REY4Q17;540REY4Q17;2-(4-amino-3-nitro-phenoxy)-ethanol;SCHEMBL1173706;DTXSID70198983;MFCD00100987;AKOS006228022;(3-NITRO-4-AMINO)PHENOXYETHANOL;AS-31446;LS-66434;2-(3-NITRO-4-AMINOPHENOXY)ETHANOL;CS-0319953;FT-0762081;3-NITRO-4-AMINOPHENOXYETHANOL [INCI];2-(4-AMINO-3-NITROPHENOXY)-1-ETHANOL;Benzenamine, 2- nitro- 4- (2- hydroxyethoxy)-;3-NITRO-4-AMINO-.BETA.-HYDROXYETHOXYBENZENE;Q27261149

Chemical Property of 2-(4-Amino-3-nitrophenoxy)ethanol

Chemical Property:

• Vapor Pressure: 3.79E-08mmHg at 25°C
• Boiling Point: 429.7°Cat760mmHg
• Flash Point: 213.7°C
• PSA: 101.30000
• Density: 1.399g/cm³
• LogP: 1.65250
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 198.06405680
• Heavy Atom Count: 14
• Complexity: 194

Purity/Quality:

98% ^*data from raw suppliers

2-(4-Amino-3-nitrophenoxy)ethan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C(C=C1OCCO)[N+](=O)[O-])N

Technology Process of 2-(4-Amino-3-nitrophenoxy)ethanol

There total 2 articles about 2-(4-Amino-3-nitrophenoxy)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4-hydroxy-2-nitrophenyl)-acetamide (7403-75-0) + 2-bromoethanol (540-51-2) → 2-(4-amino-3-nitrophenoxy)ethan-1-ol (50982-74-6)

Guidance literature:

With potassium hydroxide; sodium chloride; In N-methyl-acetamide; (2S)-N-methyl-1-phenylpropan-2-amine hydrate;

Reference yield:

→ 2-(4-amino-3-nitrophenoxy)ethan-1-ol (50982-74-6)

Guidance literature:

Reference yield:

2-(4-amino-3-nitrophenoxy)ethan-1-ol (50982-74-6) + tert-butyldimethylsilyl chloride (18162-48-6) → 4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-2-nitro-phenylamine

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃;

upstream raw materials:

N-(4-hydroxy-2-nitrophenyl)-acetamide

2-bromoethanol

Downstream raw materials:

4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-benzene-1,2-diamine

5-bromo-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid {2-amino-4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-phenyl}-amide

Refernces