N-ethyl-2-iodobenzamide

Base Information

• Chemical Name: N-ethyl-2-iodobenzamide
• CAS No.: 41882-26-2
• Molecular Formula: C9H10INO
• Molecular Weight: 275.089
• DSSTox Substance ID: DTXSID401313820
• Nikkaji Number: J1.123.186A
• Mol file: 41882-26-2.mol

Synonyms:N-ethyl-2-iodobenzamide;41882-26-2;2-Iodo-N-ethylbenzamide;SCHEMBL4352870;DTXSID401313820;AKOS008920011;BS-32418

Chemical Property of N-ethyl-2-iodobenzamide

Chemical Property:

• PSA: 29.10000
• LogP: 2.43180
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 274.98071
• Heavy Atom Count: 12
• Complexity: 161

Purity/Quality:

99% ^*data from raw suppliers

N-Ethyl-2-iodobenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNC(=O)C1=CC=CC=C1I

Technology Process of N-ethyl-2-iodobenzamide

There total 8 articles about N-ethyl-2-iodobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ N-ethyl-2-iodo-benzamide (41882-26-2)

Guidance literature:

Reference yield: 94.0%

2-Iodobenzoyl chloride (609-67-6) + ethylamine (75-04-7,85404-22-4) → N-ethyl-2-iodo-benzamide (41882-26-2)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 1h;

DOI:10.3390/molecules26237355

Reference yield: 77.0%

2-Iodobenzoyl chloride (609-67-6) → N-ethyl-2-iodo-benzamide (41882-26-2)

Guidance literature:

With ethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1080/00397911.2021.1928218

upstream raw materials:

2-Iodobenzoyl chloride

ethylamine

C₉H₉⁽²⁾HINO

2-Iodobenzoic acid

Downstream raw materials:

C₉H₉⁽²⁾HINO

N-ethylbenzamide

N-Ethyl-o-deuterobenzamide

N-Ethyl-2-(1,1-dimethylethoxy)benzamide