N,N'-dimethylethanimidamide

Base Information

• Chemical Name: N,N'-dimethylethanimidamide
• CAS No.: 4238-37-3
• Molecular Formula: C4H10N2
• Molecular Weight: 86.1368
• DSSTox Substance ID: DTXSID60393389
• Nikkaji Number: J1.509.595D
• Mol file: 4238-37-3.mol

Synonyms:N,N'-dimethylethanimidamide;4238-37-3;N,N'-dimethylaceta-midine;DTXSID60393389;AKOS006374170

Chemical Property of N,N'-dimethylethanimidamide

Chemical Property:

• XLogP3: -0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 86.084398327
• Heavy Atom Count: 6
• Complexity: 56.6

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NC)NC

Technology Process of N,N'-dimethylethanimidamide

There total 9 articles about N,N'-dimethylethanimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

N,N,N′,1,1,1-hexamethylsilanecarboximidamide + methylamine (74-89-5) → methyltrimethylsilylamine (16513-17-0) + N,N'-dimethyl-acetamidine (4238-37-3)

Guidance literature:

at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.joc.1c02397

Reference yield:

methylamine (74-89-5) + acetonitrile (75-05-8,26809-02-9) → N,N'-dimethyl-acetamidine (4238-37-3) + methyl N-methylacetamidate (44201-67-4)

Guidance literature:

lanthanum(lll) triflate; at 20 ℃; for 72h; Cooling with liquid nitrogen; Sealed vessel;

Reference yield:

O-Ethyl thioacetate (926-67-0) + methylamine (74-89-5) → N,N'-dimethyl-acetamidine (4238-37-3)

Guidance literature:

With methylamine hydrochloride; In ethanol; Heating;

upstream raw materials:

acetyl-benzenesulfonyl-methyl-amine

methylamine hydrochloride

ethyl acetimidate hydrochloride

methylamine

Downstream raw materials:

N-(4-Chlorphenyl-carbamoyl)-N_.N'-dimethylacetamidin

N_.N'-Dimethyl-N-(4-nitrophenylcarbamoyl)-acetamidin

C₁₁H₁₅N₃O₃S

N-(Benzolsulfonylcarbamoyl)-N_.N'-dimethylacetamidin