Hydrazine, 1,2-dimethyl-1,2-diphenyl-

Base Information

• Chemical Name: Hydrazine, 1,2-dimethyl-1,2-diphenyl-
• CAS No.: 14996-70-4
• Molecular Formula: C14H16 N2
• Molecular Weight: 212.294
• NSC Number: 86538
• DSSTox Substance ID: DTXSID00164439
• Nikkaji Number: J2.599.654B
• Mol file: 14996-70-4.mol

Synonyms:14996-70-4;Hydrazine, 1,2-dimethyl-1,2-diphenyl-;Hydrazine,1,2-dimethyl-1,2-diphenyl-;1,2-dimethyl-1,2-diphenylhydrazine;NSC86538;SCHEMBL6865133;DTXSID00164439;NSC 86538;NSC-86538

Chemical Property of Hydrazine, 1,2-dimethyl-1,2-diphenyl-

Chemical Property:

• Vapor Pressure: 0.000931mmHg at 25°C
• Boiling Point: 303.4°Cat760mmHg
• Flash Point: 124.9°C
• Density: 1.098g/cm³
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 212.131348519
• Heavy Atom Count: 16
• Complexity: 171

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C1=CC=CC=C1)N(C)C2=CC=CC=C2

Technology Process of Hydrazine, 1,2-dimethyl-1,2-diphenyl-

There total 18 articles about Hydrazine, 1,2-dimethyl-1,2-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

diphenyl hydrazine (122-66-7) + methyl iodide (74-88-4) → N,N'-dimethyl-N,N'-diphenyl-hydrazine (14996-70-4)

Guidance literature:

diphenyl hydrazine; methyl iodide; With n-butyllithium; In tetrahydrofuran; hexane; at -60 - 20 ℃; for 2h;

methyl iodide; In tetrahydrofuran; hexane; for 3h; Further stages.;

DOI:10.1016/j.tet.2008.04.096

Reference yield: 86.0%

N-methylaniline (100-61-8) → N,N'-dimethyl-N,N'-diphenyl-hydrazine (14996-70-4)

Guidance literature:

With dmap; 2,2'-azobis(isobutyronitrile); copper(I) bromide; In acetonitrile; at 20 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.catcom.2014.06.025

Reference yield: 27.0%

diphenyl hydrazine (122-66-7) + methyl iodide (74-88-4) → N-methyl-N,N′-diphenylhydrazine (37682-91-0) + N,N'-dimethyl-N,N'-diphenyl-hydrazine (14996-70-4)

Guidance literature:

diphenyl hydrazine; With lithium diisopropyl amide; In tetrahydrofuran; at -40 ℃; for 2h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; Inert atmosphere;

DOI:10.1021/jo500230q

upstream raw materials:

methyllithium

diphenyl hydrazine

Azobenzene

1,4-dimethyl-1,4-diphenyl-2-tetrazine

Downstream raw materials:

N-methylaniline

N-methyl-N-nitrosoaniline

N,N,N',N'-tetramethylbenzidine

Refernces

• 1、 Ren, Linning,Wang, Manman,Fang, Benyao,Yu, Wenquan,Chang, Junbiao. "Iodine-mediated oxidative N-N coupling of secondary amines to hydrazines". . p. 3446 - 3450. Retrieved 2019.
• 2、 Yin, Dehang,Jin, Jian. "Transition-Metal-Free Dehydrogenative N–N Coupling of Secondary Amines with KI/KIO4". supporting information. p. 5646 - 5649. Retrieved 2019/08/21.