(R)-3-(Benzyloxy)-1-butyne

Base Information

Chemical Name:(R)-3-(Benzyloxy)-1-butyne
CAS No.:477288-58-7
Molecular Formula:C11H12O
Molecular Weight:160.216
Hs Code.:
DSSTox Substance ID:DTXSID70459364
Nikkaji Number:J1.910.090A
Wikidata:Q82283120
Mol file:477288-58-7.mol

Synonyms:(R)-3-(Benzyloxy)-1-butyne;CTK1C7174;477288-58-7;DTXSID70459364

Suppliers and Price of (R)-3-(Benzyloxy)-1-butyne

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R)-3-(Benzyloxy)-1-butyne

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:160.088815002
Heavy Atom Count:12
Complexity:159

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C#C)OCC1=CC=CC=C1
Isomeric SMILES:C[C@H](C#C)OCC1=CC=CC=C1

Technology Process of (R)-3-(Benzyloxy)-1-butyne

There total 2 articles about (R)-3-(Benzyloxy)-1-butyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 42969-65-3
(R)-(+)-3-butyn-2-ol

: 100-39-0
benzyl bromide

: 477288-58-7
(R)-((but-3-yn-2-yloxy)methyl)benzene

Guidance literature:: (R)-(+)-3-butyn-2-ol; With tetra-(n-butyl)ammonium iodide; sodium hydride; In tetrahydrofuran; for 0.75h;

benzyl bromide; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/S0957-4166(03)00120-4

Reference yield: 72.0%

: 90965-06-3
dimethyl 1-(1-diazo-2-oxopropyl)phosphonate

: 115458-99-6
methyl (2R)-2-(benzyloxy)propanoate

: 477288-58-7
(R)-((but-3-yn-2-yloxy)methyl)benzene

Guidance literature:: methyl (2R)-2-(benzyloxy)propanoate; With diisobutylaluminium hydride; In n-heptane; dichloromethane; at -78 ℃;

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate; With potassium carbonate; In methanol; n-heptane; dichloromethane; at 20 ℃; Further stages.;
DOI:10.1016/j.tetlet.2004.05.139

Reference yield: 80.0%

: 78-84-2
isobutyraldehyde

: 477288-58-7
(R)-((but-3-yn-2-yloxy)methyl)benzene

: 562071-90-3
(3R,4Z,6R)-6-benzyloxy-2-methylhept-4-en-3-ol

: 562071-95-8
(3S,4Z,6R)-6-benzyloxy-2-methylhept-4-en-3-ol

Guidance literature:: (R)-((but-3-yn-2-yloxy)methyl)benzene; With (-)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine; In toluene; at 20 ℃; for 0.5h;

isobutyraldehyde; In toluene; at 65 ℃; for 1h;

With quinoline; hydrogen; Lindlar's catalyst; In ethyl acetate; at 20 ℃; for 1h; under 760 Torr;
DOI:10.1016/S0957-4166(03)00120-4