4-Fluoro-2-methoxyacetophenone

Base Information

Chemical Name:4-Fluoro-2-methoxyacetophenone
CAS No.:51788-80-8
Molecular Formula:C9H9FO2
Molecular Weight:168.168
Hs Code.:2914700090
European Community (EC) Number:670-596-0
DSSTox Substance ID:DTXSID30199714
Nikkaji Number:J1.784.726K
Wikidata:Q72473868
ChEMBL ID:CHEMBL4591665
Mol file:51788-80-8.mol

Synonyms:51788-80-8;1-(4-fluoro-2-methoxyphenyl)ethanone;4-Fluoro-2-methoxyacetophenone;4'-Fluoro-2'-methoxyacetophenone;1-(4-fluoro-2-methoxyphenyl)ethan-1-one;MFCD00061143;1-(4-fluoro-2-methoxy-phenyl)-ethanone;2'-Methoxy-4'-fluoroacetophenone;4'-Fluoro-2'-methoxyacetophenone,;2-METHOXY-4-FLUOROACETOPHENONE;Ethanone, 1-(4-fluoro-2-methoxyphenyl)-;SCHEMBL1020142;CHEMBL4591665;DTXSID30199714;CK2584;STK802225;AKOS005254467;FS-1124;1-(4-fluoro-2-methoxy-phenyl)ethanone;1-(4fluoro-2-methoxy-phenyl)-ethanone;4'-Fluoro-2'-methoxyacetophenone, 97%;NCGC00332019-01;BP-11177;SY003228;A7623;AM20060157;CS-0045026;FT-0618454;FT-0618455;EN300-49319;A19710;AB01325678-02;Z330830584;2,2-[(1-methylethylidene)bis(cyclohexane-4,1-diyloxymethylene)]bisoxirane;4 inverted exclamation mark -Fluoro-2 inverted exclamation mark -methoxyacetophenone

Suppliers and Price of 4-Fluoro-2-methoxyacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4''-Fluoro-2''-methoxyacetophenone
1g
$ 75.00

SynQuest Laboratories
4'-Fluoro-2'-methoxyacetophenone 98%
1 g
$ 16.00

Matrix Scientific
4'-Fluoro-2'-methoxyacetophenone 98%
5g
$ 33.00

Matrix Scientific
4'-Fluoro-2'-methoxyacetophenone 98%
25g
$ 115.00

Matrix Scientific
4'-Fluoro-2'-methoxyacetophenone 98%
100g
$ 345.00

American Custom Chemicals Corporation
4-FLUORO-2-METHOXYACETOPHENONE 95.00%
5G
$ 928.62

American Custom Chemicals Corporation
4-FLUORO-2-METHOXYACETOPHENONE 95.00%
1G
$ 429.00

Alichem
4'-Fluoro-2'-methoxyacetophenone
1g
$ 1460.20

Alichem
4'-Fluoro-2'-methoxyacetophenone
500mg
$ 815.00

Alichem
4'-Fluoro-2'-methoxyacetophenone
250mg
$ 475.20

Total 49 raw suppliers

Chemical Property of 4-Fluoro-2-methoxyacetophenone

Chemical Property:

Melting Point:51 °C
Boiling Point:228.4 °C at 760 mmHg
Flash Point:89.4 °C
PSA：26.30000
Density:1.127g/cm³
LogP:2.03690
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:168.05865769
Heavy Atom Count:12
Complexity:170

Purity/Quality:

99%, ^*data from raw suppliers

4''-Fluoro-2''-methoxyacetophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C=C(C=C1)F)OC
Uses 4''-Fluoro-2''-methoxyacetophenone

Technology Process of 4-Fluoro-2-methoxyacetophenone

There total 5 articles about 4-Fluoro-2-methoxyacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1481-27-2
4-Fluoro-2-hydroxyacetophenone

: 74-88-4
methyl iodide

: 51788-80-8
1-(4-fluoro-2-methoxy-phenyl)-ethanone

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 20 ℃; for 2h;
DOI:10.1021/jm0304010

Reference yield: 70.0%

: 456-49-5
1-fluoro-3-methoxybenzene

: 108-24-7
acetic anhydride

: 51788-80-8
1-(4-fluoro-2-methoxy-phenyl)-ethanone

: 74457-86-6
1-(2-fluoro-4-methoxyphenyl)-1-ethanone

Guidance literature:: With lithium perchlorate; at 100 ℃; for 1h;
DOI:10.1016/S0040-4039(02)01368-0

Reference yield:

: 372-20-3
3-fluorophenol

: 51788-80-8
1-(4-fluoro-2-methoxy-phenyl)-ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / CH₂Cl₂ / 0.5 h / 20 °C

2: AlCl₃ / 0.17 h / 150 °C

3: K₂CO₃ / acetone / 12 h / 40 °C

With pyridine; aluminium trichloride; potassium carbonate; In dichloromethane; acetone; 1: Acetylation / 2: Fries rearrangement / 3: Methylation;
DOI:10.1021/jm990095j