PHENYL-PHENYLAMINO-ACETONITRILE

Base Information

• Chemical Name: PHENYL-PHENYLAMINO-ACETONITRILE
• CAS No.: 4553-59-7
• Molecular Formula: C14H12 N2
• Molecular Weight: 208.263
• Hs Code.: 2926909090
• Mol file: 4553-59-7.mol

Synonyms:Acetonitrile,anilinophenyl- (8CI); Glycinonitrile, N,2-diphenyl- (6CI,7CI);Anilinophenylacetonitrile; N,2-Diphenylglycinonitrile; NSC 403420; NSC 406219; a-(Phenylamino)benzeneacetonitrile;a-Anilino-a-phenylacetonitrile; a-Anilinophenylacetonitrile

Chemical Property of PHENYL-PHENYLAMINO-ACETONITRILE

Chemical Property:

• Vapor Pressure: 1.17E-05mmHg at 25°C
• Boiling Point: 369.7°Cat760mmHg
• Flash Point: 177.4°C
• PSA: 35.82000
• Density: 1.155g/cm³
• LogP: 3.43638

Purity/Quality:

98% ^*data from raw suppliers

2-phenyl-2-(phenylamino)acetonitrile ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T

MSDS Files:

Useful:

Technology Process of PHENYL-PHENYLAMINO-ACETONITRILE

There total 67 articles about PHENYL-PHENYLAMINO-ACETONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trimethylsilyl cyanide (7677-24-9) + benzaldehyde (100-52-7) + aniline (62-53-3) → 2-anilino-2-phenylacetonitrile (4553-59-7)

Guidance literature:

With nanoporous silica SBA-15-Ph-Pr supported sulfonic acid; at 20 ℃; for 0.0833333h; neat (no solvent);

DOI:10.1039/b911388f

Reference yield: 99.0%

trimethylsilyl cyanide (7677-24-9) + (E)-N-benzylidenebenzenamine (1750-36-3,33993-35-0,538-51-2,137431-97-1,137432-04-3) → 2-anilino-2-phenylacetonitrile (4553-59-7)

Guidance literature:

With dibutyltin dibromide; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1246/cl.2009.336

Reference yield: 98.0%

trimethylsilyl cyanide (7677-24-9) + benzylidene phenylamine (538-51-2) → 2-anilino-2-phenylacetonitrile (4553-59-7)

Guidance literature:

With [Cd₃(H₂O)₂(C₂H₂N₃)₂(SO₄)₂]; In dichloromethane; at 0 ℃; for 2h; Inert atmosphere;

DOI:10.1021/cg100865v

upstream raw materials:

hydrogen cyanide

benzylidene phenylamine

diethyl ether

potassium cyanide

Downstream raw materials:

1,2,3,4-tetraphenyl-1H-pyrrole

α-Anilino-α-phenyl-N-4-chlor-phenyl-nitron

trans-5-cyano-1,4,5-triphenylpyrrolidin-2-one

2-(N-phenyl-4-methoxybenzamido)-2-phenylacetonitrile

Refernces

• 1、 Sarma, Debajit,Ramanujachary,Stock, Norbert,Natarajan, Srinivasan. "High-throughput study of the Cu(CH3COO)2· H2O-5-nitroisophthalic acid-heterocyclic ligand system: Synthesis, structure, magnetic, and heterogeneous catalytic studies of three copper nitroisophthalates". . p. 1357 - 1369. Retrieved 2011.
• 2、 Chen, Hong,Ju, Jing,Meng, Qingpeng,Su, Jie,Lin, Cong,Zhou, Zhengyang,Li, Guobao,Wang, Weilu,Gao, Wenliang,Zeng, Chunmei,Tang, Chiu,Lin, Jianhua,Yang, Tao,Sun, Junliang. "PKU-3: An HCl-Inclusive Aluminoborate for Strecker Reaction Solved by Combining RED and PXRD". . p. 7047 - 7050. Retrieved 2015.
• 3、 Li, Qun,Liu, Wei,Mohammadnia, Majid,Song, Di,Sun, Mingzhe,Wu, Wei,Yan, Li. "Synthesis and characterization of Pd supported on methane diamine (propyl silane) functionalized Fe3O4 nanoparticles as a magnetic catalyst for synthesis of α-aminonitriles and 2-methoxy-2-phenylacetonitrile derivative via Strecker-t". . . Retrieved 2021/09/18.