beta-Diethylaminopropiophenone hydrochloride

Base Information

• Chemical Name: beta-Diethylaminopropiophenone hydrochloride
• CAS No.: 884-12-8
• Molecular Formula: C13H19NO
• Molecular Weight: 241.761
• UNII: 4EX7A5KW2J
• ChEMBL ID: CHEMBL554577
• NSC Number: 227420,70239
• Mol file: 884-12-8.mol

Synonyms:884-12-8;3-(diethylamino)-1-phenylpropan-1-one hydrochloride;beta-diethylaminopropiophenone hydrochloride;4EX7A5KW2J;CHEMBL554577;SCHEMBL10670271;NSC70239;NSC-70239;NSC227420;NSC-227420;Propiophenone, 3-(diethylamino)-, hydrochloride;1-Propanone, 3-(diethylamino)-1-phenyl-, hydrochloride;1-Propanone, 3-(diethylamino)-1-phenyl-, hydrochloride (1:1)

Chemical Property of beta-Diethylaminopropiophenone hydrochloride

Chemical Property:

• Boiling Point: 301.7°Cat760mmHg
• Flash Point: 101.4°C
• Density: 0.974g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 241.1233420
• Heavy Atom Count: 16
• Complexity: 181

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)CCC(=O)C1=CC=CC=C1.Cl

Technology Process of beta-Diethylaminopropiophenone hydrochloride

There total 5 articles about beta-Diethylaminopropiophenone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + diethyl amine hydrochloride (660-68-4) + acetophenone (98-86-2) → β-(N,N-diethylamino)propiophenone hydrochloride (884-12-8)

Guidance literature:

In ethanol; for 0.0833333h; microwave irradiation;

Reference yield: 60.0%

1,3,5-Trioxan (110-88-3) + diethyl amine hydrochloride (660-68-4) + acetophenone (98-86-2) → β-(N,N-diethylamino)propiophenone hydrochloride (884-12-8)

Guidance literature:

With water; for 0.0125h; combined microwave and ultrasound irradiation;

DOI:10.1055/s-2005-872246

Reference yield: 52.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + diethyl amine hydrochloride (660-68-4) + acetophenone (98-86-2) → β-(N,N-diethylamino)propiophenone hydrochloride (884-12-8) + Phenyl vinyl ketone (768-03-6,26742-84-7)

Guidance literature:

With triethylamine; In 1,4-dioxane; at 100 ℃;

DOI:10.1039/c5ra21304e

upstream raw materials:

formaldehyd

diethylamine

acetophenone

1,3-DIOXOLANE

Downstream raw materials:

3-diethylamino-1-phenyl-propane-1,2-dione-2-oxime

N,N-diethyl-benzenepropanamine

3-diethylamino-1-phenyl-propan-1-ol

N,N'-bis(β-benzoylethyl)-p-phenylenediamine