Propanoic acid, 2-methyl-3-oxo-3-(phenylamino)-, ethyl ester

Base Information

Chemical Name:Propanoic acid, 2-methyl-3-oxo-3-(phenylamino)-, ethyl ester
CAS No.:52629-26-2
Molecular Formula:C12H15NO3
Molecular Weight:221.256
Hs Code.:
Mol file:52629-26-2.mol

Synonyms:Isobernsteinsaeure-aethylester-anilid;2-Methyl-N-phenyl-malonamidsaeure-aethylester;Ethyl 2-methyl-3-oxo-3-(phenylamino)propanoate;Methylmalonsaeure-aethylester-anilid;2-methyl-N-phenyl-malonamic acid ethyl ester;

Suppliers and Price of Propanoic acid, 2-methyl-3-oxo-3-(phenylamino)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Propanoic acid, 2-methyl-3-oxo-3-(phenylamino)-, ethyl ester

Chemical Property:

PSA：55.40000
LogP:1.89730

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Propanoic acid, 2-methyl-3-oxo-3-(phenylamino)-, ethyl ester

There total 10 articles about Propanoic acid, 2-methyl-3-oxo-3-(phenylamino)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 50496-34-9
ethyl 2-chloroformylpropanoate

: 62-53-3
aniline

: 52629-26-2
ethyl 2-(N-phenylcarbamoyl)propanoate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 6h;
DOI:10.3762/bjoc.16.124

Reference yield:

: 62-53-3
aniline

: 609-08-5
Diethyl methylmalonate

: 620-71-3
N-(phenyl)-2-methylacetamide

: 52629-26-2
ethyl 2-(N-phenylcarbamoyl)propanoate

Guidance literature:: at 100 - 130 ℃;
DOI:10.1080/00397911.2012.717671

Reference yield:

: 2985-33-3
monoethyl methylmalonate

: 52629-26-2
ethyl 2-(N-phenylcarbamoyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 3 h / 20 °C

2: triethylamine / dichloromethane / 6 h / 0 - 20 °C

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.3762/bjoc.16.124