(R)-2-Methylbutane-2,3-diol

Base Information

Chemical Name:(R)-2-Methylbutane-2,3-diol
CAS No.:53399-77-2
Molecular Formula:C5H12O2
Molecular Weight:104.149
Hs Code.:
European Community (EC) Number:819-059-6
DSSTox Substance ID:DTXSID20489994
Nikkaji Number:J1.126.171J
Wikidata:Q76422797
Mol file:53399-77-2.mol

Synonyms:(R)-2-Methylbutane-2,3-diol;53399-77-2;(3R)-2-Methylbutane-2,3-diol;(R)-2-methyl-butane-2,3-diol;SCHEMBL2148806;DTXSID20489994;IDEOPBXRUBNYBN-SCSAIBSYSA-N;EN300-1588871

Suppliers and Price of (R)-2-Methylbutane-2,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (R)-2-Methylbutane-2,3-diol

Chemical Property:

Boiling Point:71.5 °C (9 mmHg)
PSA：40.46000
Density:0.977±0.06 g/cm3(Predicted)
LogP:0.13810
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:104.083729621
Heavy Atom Count:7
Complexity:59.1

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C)(C)O)O
Isomeric SMILES:C[C@H](C(C)(C)O)O

Technology Process of (R)-2-Methylbutane-2,3-diol

There total 1 articles about (R)-2-Methylbutane-2,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 74608-26-7
(1S)-2-hydroxy-1,2-dimethylpopylamine

: 563-80-4
3-methyl-butan-2-one

: 24347-59-9
(S)-2-methylbutane-2,3-diol

: 53399-77-2
(2R)-3-methyl-2,3-butanediol

Guidance literature:: With perchloric acid; sodium nitrite; In water; for 1h; Yields of byproduct given;

Reference yield:

: 53399-77-2
(2R)-3-methyl-2,3-butanediol

: 202409-75-4
2-chloro-3-[4-(methylsulfonyl)phenyl]-5-trifluoromethyl-pyridine

: 2-((2R)-3-hydroxy-3-methyl-2-butyloxy)-3-(4-methylsulfonyl)phenyl-5-trifluoromethylpyridine

Guidance literature:: With potassium tert-butylate; In N,N-dimethyl-formamide; at 25 ℃;
DOI:10.1016/S0960-894X(99)00264-4

Reference yield:

: 53399-77-2
(2R)-3-methyl-2,3-butanediol

: 1223498-29-0
(RS)-S-(4-{[4-{[(R)-2-hydroxy-1,2-dimethylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]-amino}phenyl)-S-methylsulfoximide

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / diethyl ether; mineral oil / 0.22 h / 0 - 20 °C

1.2: 4 h / 40 °C / cooling with ice

2.1: pyridinium p-toluenesulfonate / dichloromethane / 22 h / 20 °C

3.1: potassium fluoride; copper(l) iodide / 1-methyl-pyrrolidin-2-one; tetrahydrofuran / 2 h / 20 - 90 °C

4.1: ethanol / 6 h / 70 °C

4.2: 1.5 h / 20 °C

5.1: potassium carbonate / 1.5 h / 20 °C

With potassium fluoride; copper(l) iodide; sodium hydride; potassium carbonate; pyridinium p-toluenesulfonate; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; diethyl ether; ethanol; dichloromethane; mineral oil;