Diethyl 2,2'-(1,4-phenylenebis(oxy))diacetate

Base Information

• Chemical Name: Diethyl 2,2'-(1,4-phenylenebis(oxy))diacetate
• CAS No.: 5897-78-9
• Molecular Formula: C14H18O6
• Molecular Weight: 282.293
• DSSTox Substance ID: DTXSID90493967
• Nikkaji Number: J1.009.274D
• Wikidata: Q82340994
• Mol file: 5897-78-9.mol

Synonyms:5897-78-9;Diethyl 2,2'-(1,4-phenylenebis(oxy))diacetate;Diethyl 2,2'-[1,4-phenylenebis(oxy)]diacetate;DTXSID90493967;CS-0331691;Diethyl 2,2'-(1,4-phenylenedioxy)diacetate;Acetic acid, 2,2'-[(1,4-phenylene)bis(oxy)]bis-, 1,1'-diethyl ester

Chemical Property of Diethyl 2,2'-(1,4-phenylenebis(oxy))diacetate

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 10
• Exact Mass: 282.11033829
• Heavy Atom Count: 20
• Complexity: 266

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)COC1=CC=C(C=C1)OCC(=O)OCC

Technology Process of Diethyl 2,2'-(1,4-phenylenebis(oxy))diacetate

There total 4 articles about Diethyl 2,2'-(1,4-phenylenebis(oxy))diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

ethyl bromoacetate (105-36-2) + hydroquinone (123-31-9,8027-02-9) → (4-ethoxycarbonylmethoxy-phenoxy)-acetic acid ethyl ester (5897-78-9)

Guidance literature:

With potassium carbonate; In acetone; for 24h; Reflux;

DOI:10.1016/j.cclet.2018.12.015

Reference yield: 90.0%

ethanol (64-17-5) + 2,2'-[1,4-phenylenebis(oxy)]bisacetic acid (2245-53-6) → (4-ethoxycarbonylmethoxy-phenoxy)-acetic acid ethyl ester (5897-78-9)

Guidance literature:

With sulfuric acid; for 0.166667h; Microwave irradiation;

DOI:10.3184/030823410X12705607960277

Reference yield:

ethyl bromoacetate (105-36-2) → (4-ethoxycarbonylmethoxy-phenoxy)-acetic acid ethyl ester (5897-78-9)

Guidance literature:

With ethanol;

upstream raw materials:

ethyl bromoacetate

hydroquinone

ethanol

2,2'-[1,4-phenylenebis(oxy)]bisacetic acid

Downstream raw materials:

hydroquinone-1,4-diacetyl dihydrazide

C₄₀H₃₈O₄

C₅₂H₅₂O₈

C₅₄H₅₆O₈