1-Carbazol-9-ylpropan-1-one

Base Information

Chemical Name:1-Carbazol-9-ylpropan-1-one
CAS No.:59708-36-0
Molecular Formula:C₁₅H₁₃NO
Molecular Weight:223.274
Hs Code.:
DSSTox Substance ID:DTXSID40397087
Wikidata:Q82198138

Synonyms:9H-Carbazole, 9-(1-oxopropyl)-;59708-36-0;1-carbazol-9-ylpropan-1-one;SCHEMBL10773962;DTXSID40397087;STK926944;1-(9H-carbazol-9-yl)propan-1-one;AKOS002242825

Suppliers and Price of 1-Carbazol-9-ylpropan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-CARBAZOL-9-YL-PROPAN-1-ONE 95.00%
5MG
$ 500.39

Total 0 raw suppliers

Chemical Property of 1-Carbazol-9-ylpropan-1-one

Chemical Property:

PSA：22.00000
LogP:3.84470
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:223.099714038
Heavy Atom Count:17
Complexity:279

Purity/Quality:: 1-CARBAZOL-9-YL-PROPAN-1-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)N1C2=CC=CC=C2C3=CC=CC=C31

Technology Process of 1-Carbazol-9-ylpropan-1-one

There total 5 articles about 1-Carbazol-9-ylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 79-03-8
propionyl chloride

: 33650-07-6
potassium carbazole

: 59708-36-0
9-propionylcarbazole

Guidance literature:: With sodium carbonate; for 2h; Heating;
DOI:10.1246/bcsj.54.25

Reference yield: 52.6%

: 79-03-8
propionyl chloride

: 86-74-8,105184-46-1,97960-57-1
9H-carbazole

: 59708-36-0
9-propionylcarbazole

Guidance literature:: 9H-carbazole; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.5h;

propionyl chloride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 5h;
DOI:10.1039/d1tc02742e

Reference yield:

: 1205-40-9
N-phenyl-2-chloroaniline

: 59708-36-0
9-propionylcarbazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium t-butanolate; palladium diacetate; tri tert-butylphosphoniumtetrafluoroborate / 1,4-dioxane / 18 h / 110 °C / Inert atmosphere

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 20 °C

2.2: 5 h / 0 - 20 °C

With palladium diacetate; sodium hydride; sodium t-butanolate; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; 1,4-dioxane; mineral oil;
DOI:10.1039/d1tc02742e