(4-Chloro-3-methylpyridin-2-yl)methanol

Base Information

Chemical Name:(4-Chloro-3-methylpyridin-2-yl)methanol
CAS No.:59886-85-0
Molecular Formula:C7H8ClNO
Molecular Weight:157.6
Hs Code.:2933399990
DSSTox Substance ID:DTXSID30431267
Wikidata:Q82245116
Mol file:59886-85-0.mol

Synonyms:(4-Chloro-3-methylpyridin-2-yl)methanol;59886-85-0;4-CHLORO-2-(HYDROXYMETHYL)-3-METHYLPYRIDINE;4-chloro-2-hydroxymethyl-3-methylpyridine;SCHEMBL7984286;DTXSID30431267;IPJMZFJRPTWZTD-UHFFFAOYSA-N;4-Chloro-3-methylpyridine-2-methanol;AKOS006326861;AT37425;SB53384;CS-0378934;FT-0664717;A923424

Suppliers and Price of (4-Chloro-3-methylpyridin-2-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-2-(hydroxymethyl)-3-methylpyridine
500mg
$ 690.00

TRC
4-Chloro-2-(hydroxymethyl)-3-methylpyridine
1g
$ 1230.00

Biosynth Carbosynth
4-Chloro-2-(hydroxymethyl)-3-methylpyridine
1 g
$ 1528.80

Biosynth Carbosynth
4-Chloro-2-(hydroxymethyl)-3-methylpyridine
500 mg
$ 840.00

Biosynth Carbosynth
4-Chloro-2-(hydroxymethyl)-3-methylpyridine
250 mg
$ 462.50

Biosynth Carbosynth
4-Chloro-2-(hydroxymethyl)-3-methylpyridine
100 mg
$ 255.00

Biosynth Carbosynth
4-Chloro-2-(hydroxymethyl)-3-methylpyridine
50 mg
$ 140.00

American Custom Chemicals Corporation
(4-CHLORO-3-METHYLPYRIDIN-2-YL)METHANOL 95.00%
5MG
$ 505.13

Alichem
4-Chloro-3-methylpyridine-2-methanol
1g
$ 2866.05

Alichem
4-Chloro-3-methylpyridine-2-methanol
250mg
$ 960.40

Total 11 raw suppliers

Chemical Property of (4-Chloro-3-methylpyridin-2-yl)methanol

Chemical Property:

Melting Point:46-47 °C(Solv: ligroine (8032-32-4))
Boiling Point:262.3±35.0 °C(Predicted)
PKA:13.15±0.10(Predicted)
PSA：33.12000
Density:1.263±0.06 g/cm3(Predicted)
LogP:1.53570
Solubility.:Chloroform, Dichloromethane, Methanol
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:157.0294416
Heavy Atom Count:10
Complexity:110

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-2-(hydroxymethyl)-3-methylpyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CN=C1CO)Cl
Uses 4-Chloro-2-(hydroxymethyl)-3-methylpyridine can act as intermediate used in the preparation of potential antineoplastic agents

Technology Process of (4-Chloro-3-methylpyridin-2-yl)methanol

There total 4 articles about (4-Chloro-3-methylpyridin-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.3%

: 59886-90-7
4-chloro-2,3-dimethylpyridine-N-oxide

: 59886-85-0
2-hydroxymethyl-4-chloro-3-methylpyridine

Guidance literature:: 4-chloro-2,3-dimethylpyridine-N-oxide; With acetic anhydride; at 110 ℃; for 1h;

With sodium hydroxide; In ethanol; at 80 ℃; for 3h;

Reference yield:

: 59886-84-9
(4-chloro-3-methylpyridin-2-yl)methyl acetate

: 59886-85-0
2-hydroxymethyl-4-chloro-3-methylpyridine

Guidance literature:: With sodium hydroxide; In water; at 25 ℃; for 1h;

Reference yield:

: 37699-43-7
2,3-dimethyl-4-nitropyridine N-oxide

: 59886-85-0
2-hydroxymethyl-4-chloro-3-methylpyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / POCl₃ / CH₂Cl₂; dimethylformamide / 12 h / 25 °C

2: 5 h / 120 °C

3: NaOH / H₂O / 1 h / 25 °C

With sodium hydroxide; trichlorophosphate; In dichloromethane; water; N,N-dimethyl-formamide;