Benzenepropanoic acid, b-acetyl-

Base Information

• Chemical Name: Benzenepropanoic acid, b-acetyl-
• CAS No.: 6049-50-9
• Molecular Formula: C11H12O3
• Molecular Weight: 192.214
• Mol file: 6049-50-9.mol

Synonyms:3-Phenyl-pentanon-(4)-saeure-(1);3-Phenyllaevulinsaeure;4-oxo-3-phenylpentanoic acid;3-Phenyl-laevulinsaeure;

Chemical Property of Benzenepropanoic acid, b-acetyl-

Chemical Property:

• PSA: 54.37000
• LogP: 1.83390

Purity/Quality:

95% ^*data from raw suppliers

4-OXO-3-PHENYL-PENTANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenepropanoic acid, b-acetyl-

There total 14 articles about Benzenepropanoic acid, b-acetyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Methyl 4-oxo-3-phenylpentanoate (25359-49-3) → 4-Oxo-3-phenylpentanoic acid (6049-50-9)

Guidance literature:

With potassium hydroxide; In methanol; water; at 20 ℃; for 1h;

DOI:10.1021/ja001395p

Reference yield: 69.0%

3-phenyl-4-oxopentanoic acid ethyl ester (63795-90-4) → 4-Oxo-3-phenylpentanoic acid (6049-50-9)

Guidance literature:

With potassium hydroxide; In methanol; for 4h; Ambient temperature;

Reference yield: 61.0%

(E)-4-phenyl-3-pentenoic acid (223243-86-5) → 4-Oxo-3-phenylpentanoic acid (6049-50-9)

Guidance literature:

With silver tetrafluoroborate; 1-fluoro-3,3-dimethyl-1,3-dihydro-1λ³-benzo[d][1,2]iodaoxole; In dichloromethane; at 40 ℃; for 1h; Schlenk technique; Glovebox; Sealed tube;

DOI:10.1039/c8ob02236d

upstream raw materials:

2-carboxy-3-phenyl-4-oxopentanoic acid

3-phenyl-4-oxopentanoic acid ethyl ester

4-phenyl-5-methyl-1,3-dihydro-1H-pyrrol-2-one

3-Phenyllevulinic Acid Dimethylamide

Downstream raw materials:

1-diazo-4-phenylhexane-2,5-dione

cis-5-Methyl-4-phenyl-4,5-dihydro-2(3H)-furanone

3-(2-cyanoethyl)-3-phenyl-4-oxopentanoic acid

5-methyl-4-phenylfuran-2(5H)-one