1-(4-Bromophenyl)-1,7,9-triazaspiro[4.5]decane-2,6,8,10-tetrone

Base Information

Chemical Name:1-(4-Bromophenyl)-1,7,9-triazaspiro[4.5]decane-2,6,8,10-tetrone
CAS No.:620627-99-8
Molecular Formula:C13H10BrN3O4
Molecular Weight:352.144
Hs Code.:
DSSTox Substance ID:DTXSID90431703
Wikidata:Q82245659
Pharos Ligand ID:GVYRUZVNS1KH
ChEMBL ID:CHEMBL181372

Synonyms:CHEMBL181372;1-(4-bromophenyl)-1,7,9-triazaspiro[4.5]decane-2,6,8,10-tetrone;620627-99-8;SCHEMBL6731606;DTXSID90431703;BDBM50160844;1-(4-Bromo-phenyl)-1,7,9-triaza-spiro[4.5]decane-2,6,8,10-tetraone

Suppliers and Price of 1-(4-Bromophenyl)-1,7,9-triazaspiro[4.5]decane-2,6,8,10-tetrone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(4-Bromophenyl)-1,7,9-triazaspiro[4.5]decane-2,6,8,10-tetrone

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:350.98547
Heavy Atom Count:21
Complexity:508

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(C(=O)NC(=O)NC2=O)N(C1=O)C3=CC=C(C=C3)Br

Technology Process of 1-(4-Bromophenyl)-1,7,9-triazaspiro[4.5]decane-2,6,8,10-tetrone

There total 3 articles about 1-(4-Bromophenyl)-1,7,9-triazaspiro[4.5]decane-2,6,8,10-tetrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 5683-27-2
N-(4-bromophenyl)-5,5-diethoxycarbonylpyrrolidone

: 57-13-6
urea

: 620627-99-8
1-(4-bromophenyl)-1,7,9-triazaspiro[4,5]decane-2,6,8,10-tetraone

Guidance literature:: urea; With ethanol; sodium; at 20 ℃; for 0.5h;

N-(4-bromophenyl)-5,5-diethoxycarbonylpyrrolidone; In ethanol; at 80 ℃; for 5h;

Reference yield:

: 5500-48-1
diethyl 2-[(4-bromophenyl)amino]malonate

: 620627-99-8
1-(4-bromophenyl)-1,7,9-triazaspiro[4,5]decane-2,6,8,10-tetraone

Guidance literature:: Multi-step reaction with 2 steps

1: NaOEt / ethanol / 3 h

2: NaOEt / ethanol / 80 °C

With sodium ethanolate; In ethanol;
DOI:10.1016/j.bmcl.2004.12.016

Reference yield:

: 106-40-1
4-bromo-aniline

: 620627-99-8
1-(4-bromophenyl)-1,7,9-triazaspiro[4,5]decane-2,6,8,10-tetraone

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide / 100 °C

2: NaOEt / ethanol / 3 h

3: NaOEt / ethanol / 80 °C

With sodium ethanolate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.12.016