5683-27-2 Usage
Uses
Used in Organic Synthesis:
2,2-Pyrrolidinedicarboxylic acid, 1-(4-bromophenyl)-5-oxo-, diethyl ester is used as a building block in organic synthesis for the creation of various compounds. Its unique molecular structure allows for the formation of a wide range of products, making it a valuable component in the synthesis process.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2,2-Pyrrolidinedicarboxylic acid, 1-(4-bromophenyl)-5-oxo-, diethyl ester is employed as a key intermediate in the development of pharmaceuticals and biologically active compounds. Its versatility and reactivity enable the synthesis of a variety of drug candidates, contributing to the advancement of new treatments and therapies.
Used in Pharmaceutical Industry:
2,2-Pyrrolidinedicarboxylic acid, 1-(4-bromophenyl)-5-oxo-, diethyl ester is used as a crucial component in the pharmaceutical industry for the synthesis of various drugs. Its role in the development of new medications is significant, as it can be incorporated into the molecular structures of potential therapeutic agents, enhancing their efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 5683-27-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,8 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5683-27:
(6*5)+(5*6)+(4*8)+(3*3)+(2*2)+(1*7)=112
112 % 10 = 2
So 5683-27-2 is a valid CAS Registry Number.
5683-27-2Relevant academic research and scientific papers
Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13)
Kim, Soong-Hoon,Pudzianowski, Andrew T.,Leavitt, Kenneth J.,Barbosa, Joseph,McDonnell, Patricia A.,Metzler, William J.,Rankin, Bruce M.,Liu, Richard,Vaccaro, Wayne,Pitts, William
, p. 1101 - 1106 (2007/10/03)
Computer aided drug design led to a new class of spiro-barbiturates (e.g., 4a, MMP-13 Ki = 4.7 nM) that are potent inhibitors of MMP-13.
SPIROBARBITURIC ACID DERIVATIVES USEFUL AS INHIBITORS OF MATRIX METALLOPROTEASES
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Page/Page column 46; 47, (2010/02/07)
Compound having the formula (I),wherein A, B and D are O or S; R1a and R1b are H, C1-4 alkyl, C2-4alkenyl; X is-NR2-,-S-,-S(=O)-, or -S(O)2-; G1, G2 and G3
