Methylenebis(diphenylarsine)

Base Information

• Chemical Name: Methylenebis(diphenylarsine)
• CAS No.: 21892-63-7
• Molecular Formula: C25H22 As2
• Molecular Weight: 472.293
• Hs Code.: 2931900090
• European Community (EC) Number: 244-639-5
• NSC Number: 158922
• UNII: ZX5A8WAC34
• DSSTox Substance ID: DTXSID00176294
• Nikkaji Number: J225.472G
• Wikidata: Q83046623
• Mol file: 21892-63-7.mol

Synonyms:Methylenebis(diphenylarsine);21892-63-7;diphenylarsanylmethyl(diphenyl)arsane;bis(diphenylarsino)methane;ZX5A8WAC34;NSC-158922;NSC158922;BENZYLCYANIDE-13C;UNII-ZX5A8WAC34;Bis[diphenylarsine] methane;ANTINEOPLASTIC-158922;DTXSID00176294;EINECS 244-639-5;AKOS024429496;NSC 158922;BIS-(1 2-DIPHENYLARSENO)METHANE;FT-0638159;1,1'-METHYLENEBIS(1,1-DIPHENYLARSINE);ARSINE, 1,1'-METHYLENEBIS(1,1-DIPHENYL-

Chemical Property of Methylenebis(diphenylarsine)

Chemical Property:

• Vapor Pressure: 8.66E-10mmHg at 25°C
• Boiling Point: 504°Cat760mmHg
• Flash Point: 259.4°C
• PSA: 0.00000
• Density: g/cm³
• LogP: 3.14400
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 6
• Exact Mass: 472.01534
• Heavy Atom Count: 27
• Complexity: 325

Purity/Quality:

99% ^*data from raw suppliers

[(DIPHENYLARSANYL)METHYL]DIPHENYLARSANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)[As](C[As](C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of Methylenebis(diphenylarsine)

There total 12 articles about Methylenebis(diphenylarsine) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

dichloromethane (75-09-2) + Potassium Diphenylarsenide (21498-51-1) → triphenyl-arsane (603-32-7) + bis(diphenylarsino)methane (21892-63-7)

Guidance literature:

In tetrahydrofuran; for 1.5h; Ambient temperature;

Reference yield: 54.0%

dichloromethane (75-09-2) + hexaphenylcyclohexaarsane (20738-31-2) + phenyllithium (591-51-5) → bis(diphenylarsino)methane (21892-63-7)

Guidance literature:

hexaphenylcyclohexaarsane; phenyllithium; In tetrahydrofuran; at 0 - 20 ℃; for 2h; Inert atmosphere;

dichloromethane; In tetrahydrofuran; at 0 - 20 ℃; for 19h; Inert atmosphere;

DOI:10.1246/cl.190540

Reference yield:

phenylhydrazine (100-63-0) → bis(diphenylarsino)methane (21892-63-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) 80 percent arsenic acid, CuO, 2.) conc. HCl / 1.) H₂O, 70 deg C, 2 h, 2.) CCl₄, 5 min

2: 76 percent / PhLi / tetrahydrofuran; benzene; diethyl ether / 1.) -120 deg C, 2.) -120 deg C to r.t.

3: 1.) BiLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) THF, hexane, -70 deg C to r.t.

With hydrogenchloride; n-butyllithium; orthoarsenic acid; phenyllithium; copper(II) oxide; In tetrahydrofuran; diethyl ether; benzene;

upstream raw materials:

methylenebis(dichloroarsine)

(diphenylarsino-methyl)-diphenyl-arsine oxide

bromobenzene

dichloromethane

Downstream raw materials:

C₂₅H₂₂As₂F₄

diphenylmethylarsine

Diphenylbutylarsine

C₂₅H₂₂As₂S₂