Morpholine, 4-[2-isocyano-1-oxo-3-phenyl-2-(phenylmethyl)propyl]-

Base Information

Chemical Name:Morpholine, 4-[2-isocyano-1-oxo-3-phenyl-2-(phenylmethyl)propyl]-
CAS No.:63348-64-1
Molecular Formula:C21H22N2O2
Molecular Weight:334.418
Hs Code.:

Synonyms:

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Chemical Property of Morpholine, 4-[2-isocyano-1-oxo-3-phenyl-2-(phenylmethyl)propyl]-

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Technology Process of Morpholine, 4-[2-isocyano-1-oxo-3-phenyl-2-(phenylmethyl)propyl]-

There total 1 articles about Morpholine, 4-[2-isocyano-1-oxo-3-phenyl-2-(phenylmethyl)propyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-39-0
benzyl bromide

: 67434-29-1
isocyanoacetylmorpholine

: 63348-64-1
4-(2-benzyl-2-isocyano-3-phenyl-propionyl)-morpholine

Guidance literature:: With sodium hydride; In tetrahydrofuran; for 1.5h; Ambient temperature;
DOI:10.1055/s-1977-24337

Reference yield: 86.0%

: 5765-65-1
4-(benzoyloxy)morpholine

: 63348-64-1
4-(2-benzyl-2-isocyano-3-phenyl-propionyl)-morpholine

: C₂₅H₂₉N₃O₃

Guidance literature:: With palladium diacetate; caesium carbonate; triphenylphosphine; Trimethylacetic acid; In 1,4-dioxane; at 110 ℃; Inert atmosphere;
DOI:10.1039/c9ra09139d

Reference yield:

: 612-55-5
2-iodonaphthalene

: 63348-64-1
4-(2-benzyl-2-isocyano-3-phenyl-propionyl)-morpholine

: C₃₁H₂₈N₂O₂

: C₃₁H₂₈N₂O₂

Guidance literature:: With C₃₆H₃₀NO₂P; water; palladium diacetate; caesium carbonate; Trimethylacetic acid; In 1,4-dioxane; at 80 ℃; for 1h; Overall yield = 78 %; enantioselective reaction; Inert atmosphere;
DOI:10.1021/acscatal.7b00731