2-(2,4,5-Trimethoxyphenyl)-4,4-dimethyl-2-oxazoline

Base Information

Chemical Name:2-(2,4,5-Trimethoxyphenyl)-4,4-dimethyl-2-oxazoline
CAS No.:64957-88-6
Molecular Formula:C14H19NO4
Molecular Weight:265.309
Hs Code.:
DSSTox Substance ID:DTXSID001192149
Nikkaji Number:J617.683F

Synonyms:64957-88-6;SCHEMBL2150715;MVSJWXNKSXFJOA-UHFFFAOYSA-N;4,5-dihydro-4,4-dimethyl-2-(2,4,5-trimethoxyphenyl)Oxazole;DTXSID001192149;2-(2,4,5-trimethoxyphenyl)-4,4-dimethyl-2-oxazoline;1-[(4,5-Dihydro-4,4-dimethyloxazol)-2-yl]-2,4,5-trimethoxybenzene

Suppliers and Price of 2-(2,4,5-Trimethoxyphenyl)-4,4-dimethyl-2-oxazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2,4,5-Trimethoxyphenyl)-4,4-dimethyl-2-oxazoline

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:265.13140809
Heavy Atom Count:19
Complexity:342

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(COC(=N1)C2=CC(=C(C=C2OC)OC)OC)C

Technology Process of 2-(2,4,5-Trimethoxyphenyl)-4,4-dimethyl-2-oxazoline

There total 2 articles about 2-(2,4,5-Trimethoxyphenyl)-4,4-dimethyl-2-oxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 60-29-7,927820-24-4
diethyl ether

: 573-11-5
2,3,4-Trimethoxy-benzoic acid

: 124-68-5
2-Amino-2-methyl-1-propanol

: 64957-88-6
4,4-dimethyl-2-(2,4,5-trimethoxy-phenyl)-4,5-dihydro-oxazole

Guidance literature:: With thionyl chloride; In dichloromethane;

Reference yield:

: 490-64-2
asaronic acid

: 124-68-5
2-Amino-2-methyl-1-propanol

: 64957-88-6
4,4-dimethyl-2-(2,4,5-trimethoxy-phenyl)-4,5-dihydro-oxazole

Guidance literature:: Multistep reaction; (i) SOCl₂, (ii) /BRN= 505979/, CH₂Cl₂, (iii) SOCl₂;
DOI:10.1021/jo00401a018

Reference yield: 76.0%

: 64957-88-6
4,4-dimethyl-2-(2,4,5-trimethoxy-phenyl)-4,5-dihydro-oxazole

: 34824-58-3
2-(2-bromophenyl)-1,3-dioxolan

: 451478-48-1
2-(2-(2-[1,3]dioxol-2-ylphenyl)-4,5-dimethoxyphenyl)-4,4-dimethyl-4,5-dihydro[1,3]oxazole

Guidance literature:: 2-(2-bromophenyl)-1,3-dioxolan; With 1,2-dibromo-1,1,2,2-tetrafluoroethane; magnesium; In tetrahydrofuran; for 1h;

4,4-dimethyl-2-(2,4,5-trimethoxy-phenyl)-4,5-dihydro-oxazole; In tetrahydrofuran; Further stages.;
DOI:10.1021/jo0202379