Cyclohexanol, 2-(1-cyclohexen-1-yl)-

Base Information

• Chemical Name: Cyclohexanol, 2-(1-cyclohexen-1-yl)-
• CAS No.: 65181-96-6
• Molecular Formula: C12H20O
• Molecular Weight: 180.29
• Mol file: 65181-96-6.mol

Synonyms:

Chemical Property of Cyclohexanol, 2-(1-cyclohexen-1-yl)-

Chemical Property:

• PSA: 20.23000
• LogP: 3.03790

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclohexanol, 2-(1-cyclohexen-1-yl)-

There total 12 articles about Cyclohexanol, 2-(1-cyclohexen-1-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

2-(1-cyclohexenyl)cyclohexanone (1502-22-3) → 2-(cyclohexen-1-yl)-1-cyclohexanol (65181-96-6)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 0 - 25 ℃;

DOI:10.1039/c4md00454j

Reference yield:

cyclohexanol (108-93-0) → cyclohexenone (930-68-7) + 2-(1-cyclohexenyl)cyclohexanone (1502-22-3) + 2-cyclohexylidenecyclohexanone (1011-12-7) + d,l-2-cyclohexylcyclohexanone (90-42-6) + 2-(cyclohexen-1-yl)-1-cyclohexanol (65181-96-6) + 2-cyclohexylidene-cyclohexanol (100314-24-7) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + cyclohexene (110-83-8) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) + phenol (108-95-2,27073-41-2)

Guidance literature:

With T-2130; at 250 - 290 ℃; under 760.051 Torr;

DOI:10.1016/j.apcata.2010.10.036

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → 1-cyclohexyl-1-cyclohexene (3282-54-0) + cyclohexane (110-82-7,25012-93-5) + 2-(cyclohexen-1-yl)-1-cyclohexanol (65181-96-6) + 2-cyclohexylcyclohexanol (6531-86-8) + cyclohexanol (108-93-0)

Guidance literature:

With trifluorormethanesulfonic acid; [Ru(η⁵-C5H5)(6,6'-diamino-2,2'-bipyridine)]2(OTf)2; hydrogen; at 175 ℃; for 10h; under 46544.6 Torr; Schlenk technique; Inert atmosphere; Autoclave;

DOI:10.1021/om400871v

upstream raw materials:

2-(1-cyclohexenyl)cyclohexanone

cyclohexanone

2-Chlorocyclohexanone

toluene

Downstream raw materials:

Adipic acid

6-cyclohex-1-enyl-6-oxo-hexanoic acid

7-cyclohexyl-oxepan-2-one

6-cyclohexyl-6-hydroxy-hexanoic acid

Refernces

• 1、 Zhao, Yang,Weix, Daniel J.. "Enantioselective cross-coupling of meso -epoxides with aryl halides". supporting information. p. 3327 - 3340. Retrieved 2015/03/30.
• 2、 Dimondo, Domenico,Thibault, Michelle E.,Britten, James,Schlaf, Marcel. "Comparison of the catalytic activity of [(η5-C 5H5)Ru(2,2′-bipyridine)(L)]OTf versus [(η5-C5H5)Ru(6,6′-diamino-2,2′- bipyridine)(L)]OTf (L = labile ligand) in the hydrogenation of cyclohexanone. Evidence for the presence of a metal-ligand bifunctional mechanism under acidic conditions". . p. 6541 - 6554. Retrieved 2013/12/04.