10-FORMYLFOLIC ACID (25 MG)

Base Information

• Chemical Name: 10-FORMYLFOLIC ACID (25 MG)
• CAS No.: 134-05-4
• Molecular Formula: C20H19N7O7
• Molecular Weight: 469.414
• Hs Code.: 2936299055
• Mol file: 134-05-4.mol

Synonyms:(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-formyl-amino]benzoyl]amino]pentanedioic acid;Linearolactone;

Chemical Property of 10-FORMYLFOLIC ACID (25 MG)

Chemical Property:

• Refractive Index: 1.748
• PKA: 3.41±0.10(Predicted)
• PSA: 221.56000
• Density: 1.67g/cm³
• LogP: 1.11410
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly, Heated, Sonicated), Methanol (Very Slightly, Heated)

Purity/Quality:

98%Min ^*data from raw suppliers

10-FormylFolicAcid(>90%) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 10-Formyl Folic Acid is a Folic acid (F680300) derivative (or folate) found in daily dietary intake that is often used in cancer risk correlation studies. As a Folic acid (F680300) derivative (or folate) found in daily dietary intake, 10-Formylfolic Acid is often used in cancer risk correlation studies.

Technology Process of 10-FORMYLFOLIC ACID (25 MG)

There total 3 articles about 10-FORMYLFOLIC ACID (25 MG) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formic acid (64-18-6) + Folic acid → N10-formylfolic acid (134-05-4)

Guidance literature:

DOI:10.1021/ja01182a526

Reference yield:

formic acid (64-18-6) + folate (59-30-3) → 10-formyl folic acid (134-05-4) + 10-formyl pteroic acid

Guidance literature:

With magnesium sulfate; for 1h; Reflux;

DOI:10.1039/c4dt00081a

Reference yield:

→ N-{4-[(2-amino-4-oxo-3,4-dihydro-pteridin-6-ylmethyl)-formyl-amino]-benzoyl}-glutamic acid (134-05-4)

Guidance literature:

Folsaeure, Ameisensaeure + Essigsaeureanhydrid;

upstream raw materials:

formic acid

folate

Downstream raw materials:

folinic acid

10-formyltetrahydrofolate

(6RS)-5,10-diformyl-5,6,7,8-tetrahydrofolic acid